m-PEG5-SH
Based on 1 Customer Validation
m-PEG5-SH is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 524030-00-0
- 分子式: C11H24O5S
- 分子量:268.37
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保管条件:
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 524030-00-0
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性状 Liquid (Density: 1.048 g/cm3)
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分子量 268.37
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分子式 C11H24O5S
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Color Colorless to light yellow
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SMILES
COCCOCCOCCOCCOCCS
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
溶剤 & 溶解度
DMSO : ≥ 100 mg/mL (372.62 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (265 KB)
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SDS (624 KB)
- English - EN (624 KB)
- Français - FR (624 KB)
- Deutsch - DE (624 KB)
- Norwegian - NO (624 KB)
- Español - ES (624 KB)
- Swedish - SV (624 KB)
- Italian - IT (624 KB)
- Korean - KR (624 KB)
- Portuguese - PT (624 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7262 mL | 18.6310 mL | 37.2620 mL | 93.1550 mL |
| 5 mM | 0.7452 mL | 3.7262 mL | 7.4524 mL | 18.6310 mL | |
| 10 mM | 0.3726 mL | 1.8631 mL | 3.7262 mL | 9.3155 mL | |
| 15 mM | 0.2484 mL | 1.2421 mL | 2.4841 mL | 6.2103 mL | |
| 20 mM | 0.1863 mL | 0.9315 mL | 1.8631 mL | 4.6577 mL | |
| 25 mM | 0.1490 mL | 0.7452 mL | 1.4905 mL | 3.7262 mL | |
| 30 mM | 0.1242 mL | 0.6210 mL | 1.2421 mL | 3.1052 mL | |
| 40 mM | 0.0932 mL | 0.4658 mL | 0.9315 mL | 2.3289 mL | |
| 50 mM | 0.0745 mL | 0.3726 mL | 0.7452 mL | 1.8631 mL | |
| 60 mM | 0.0621 mL | 0.3105 mL | 0.6210 mL | 1.5526 mL | |
| 80 mM | 0.0466 mL | 0.2329 mL | 0.4658 mL | 1.1644 mL | |
| 100 mM | 0.0373 mL | 0.1863 mL | 0.3726 mL | 0.9315 mL |