MAC glucuronide linker-1
Based on 1 Customer Validation
MAC glucuronide linker-1 is a claevable ADC linker for antibody-agent-conjugations (ADCs).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 96.36%
- CAS 番号: 2222981-71-5
- 分子式: C42H47N3O17S
- 分子量:897.90
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保管条件:
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
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Help & FAQs
生物活性
製品説明
IC50 & Target
|
Glycosidase Cleavable Linker |
Cleavable Linker |
体外実験
ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 2222981-71-5
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性状 Solid
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分子量 897.90
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分子式 C42H47N3O17S
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Color White to off-white
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SMILES
O=C(OC)[C@@H](O1)[C@@H](OC(C)=O)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@@H]1OC2=CC=C(COC(NCCS(=O)(C)=O)=O)C=C2NC(CN(C(OCC3C4=C(C5=C3C=CC=C5)C=CC=C4)=O)C)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (111.37 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (249 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.1137 mL | 5.5685 mL | 11.1371 mL | 27.8427 mL |
| 5 mM | 0.2227 mL | 1.1137 mL | 2.2274 mL | 5.5685 mL | |
| 10 mM | 0.1114 mL | 0.5569 mL | 1.1137 mL | 2.7843 mL | |
| 15 mM | 0.0742 mL | 0.3712 mL | 0.7425 mL | 1.8562 mL | |
| 20 mM | 0.0557 mL | 0.2784 mL | 0.5569 mL | 1.3921 mL | |
| 25 mM | 0.0445 mL | 0.2227 mL | 0.4455 mL | 1.1137 mL | |
| 30 mM | 0.0371 mL | 0.1856 mL | 0.3712 mL | 0.9281 mL | |
| 40 mM | 0.0278 mL | 0.1392 mL | 0.2784 mL | 0.6961 mL | |
| 50 mM | 0.0223 mL | 0.1114 mL | 0.2227 mL | 0.5569 mL | |
| 60 mM | 0.0186 mL | 0.0928 mL | 0.1856 mL | 0.4640 mL | |
| 80 mM | 0.0139 mL | 0.0696 mL | 0.1392 mL | 0.3480 mL | |
| 100 mM | 0.0111 mL | 0.0557 mL | 0.1114 mL | 0.2784 mL |
MAC glucuronide linker-1 関連分類
HY-44221 関連分類
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