Mal-C2-NHS ester
Based on 1 Customer Validation
Mal-C2-NHS ester is a non-cleavable ADC linker used in the synthesis of antibody-drug conjugates (ADCs).
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研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.30%
- CAS 番号: 103750-03-4
- 分子式: C13H14N2O6
- 分子量:294.26
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
製品説明
IC50 & Target
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Non-cleavable Linker |
体外実験
Mal-C2-NHS ester is a non-degradable ADC linker used for the synthesis of antibody-drug conjugates (ADCs)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
化学情報
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CAS 番号 103750-03-4
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性状 Solid
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分子量 294.26
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分子式 C13H14N2O6
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Color White to light yellow
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SMILES
O=C(ON1C(CCC1=O)=O)CCCCN2C(C=CC2=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (339.84 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (393 KB)
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- Français - FR (393 KB)
- Deutsch - DE (393 KB)
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- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.3984 mL | 16.9918 mL | 33.9836 mL | 84.9589 mL |
| 5 mM | 0.6797 mL | 3.3984 mL | 6.7967 mL | 16.9918 mL | |
| 10 mM | 0.3398 mL | 1.6992 mL | 3.3984 mL | 8.4959 mL | |
| 15 mM | 0.2266 mL | 1.1328 mL | 2.2656 mL | 5.6639 mL | |
| 20 mM | 0.1699 mL | 0.8496 mL | 1.6992 mL | 4.2479 mL | |
| 25 mM | 0.1359 mL | 0.6797 mL | 1.3593 mL | 3.3984 mL | |
| 30 mM | 0.1133 mL | 0.5664 mL | 1.1328 mL | 2.8320 mL | |
| 40 mM | 0.0850 mL | 0.4248 mL | 0.8496 mL | 2.1240 mL | |
| 50 mM | 0.0680 mL | 0.3398 mL | 0.6797 mL | 1.6992 mL | |
| 60 mM | 0.0566 mL | 0.2832 mL | 0.5664 mL | 1.4160 mL | |
| 80 mM | 0.0425 mL | 0.2124 mL | 0.4248 mL | 1.0620 mL | |
| 100 mM | 0.0340 mL | 0.1699 mL | 0.3398 mL | 0.8496 mL |