Mal-PEG2-NHS
Based on 1 Customer Validation
Mal-PEG2-NHS is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.0%
- CAS 番号: 329364-72-9
- 分子式: C14H16N2O8
- 分子量:340.29
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保管条件:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 329364-72-9
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性状 Solid-Liquid Mixture
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分子量 340.29
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分子式 C14H16N2O8
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Color Colorless to light yellow
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SMILES
O=C1C=CC(N1CCOCCOCC(ON2C(CCC2=O)=O)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
DMSO : 100 mg/mL (293.87 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.9387 mL | 14.6933 mL | 29.3867 mL | 73.4667 mL |
| 5 mM | 0.5877 mL | 2.9387 mL | 5.8773 mL | 14.6933 mL | |
| 10 mM | 0.2939 mL | 1.4693 mL | 2.9387 mL | 7.3467 mL | |
| 15 mM | 0.1959 mL | 0.9796 mL | 1.9591 mL | 4.8978 mL | |
| 20 mM | 0.1469 mL | 0.7347 mL | 1.4693 mL | 3.6733 mL | |
| 25 mM | 0.1175 mL | 0.5877 mL | 1.1755 mL | 2.9387 mL | |
| 30 mM | 0.0980 mL | 0.4898 mL | 0.9796 mL | 2.4489 mL | |
| 40 mM | 0.0735 mL | 0.3673 mL | 0.7347 mL | 1.8367 mL | |
| 50 mM | 0.0588 mL | 0.2939 mL | 0.5877 mL | 1.4693 mL | |
| 60 mM | 0.0490 mL | 0.2449 mL | 0.4898 mL | 1.2244 mL | |
| 80 mM | 0.0367 mL | 0.1837 mL | 0.3673 mL | 0.9183 mL | |
| 100 mM | 0.0294 mL | 0.1469 mL | 0.2939 mL | 0.7347 mL |