Mal-PEG8-Boc
Based on 1 Customer Validation
Mal-PEG8-Boc is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 95.08%
- CAS 番号: 2055048-43-4
- 分子式: C27H47NO12
- 分子量:577.66
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保管条件:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
Alkyl/ether |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2055048-43-4
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性状 Oil
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分子量 577.66
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分子式 C27H47NO12
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)CCOCCOCCOCCOCCOCCOCCOCCOCCN1C(C=CC1=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
溶剤 & 溶解度
DMSO : 100 mg/mL (173.11 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (stored under nitrogen). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7311 mL | 8.6556 mL | 17.3112 mL | 43.2781 mL |
| 5 mM | 0.3462 mL | 1.7311 mL | 3.4622 mL | 8.6556 mL | |
| 10 mM | 0.1731 mL | 0.8656 mL | 1.7311 mL | 4.3278 mL | |
| 15 mM | 0.1154 mL | 0.5770 mL | 1.1541 mL | 2.8852 mL | |
| 20 mM | 0.0866 mL | 0.4328 mL | 0.8656 mL | 2.1639 mL | |
| 25 mM | 0.0692 mL | 0.3462 mL | 0.6924 mL | 1.7311 mL | |
| 30 mM | 0.0577 mL | 0.2885 mL | 0.5770 mL | 1.4426 mL | |
| 40 mM | 0.0433 mL | 0.2164 mL | 0.4328 mL | 1.0820 mL | |
| 50 mM | 0.0346 mL | 0.1731 mL | 0.3462 mL | 0.8656 mL | |
| 60 mM | 0.0289 mL | 0.1443 mL | 0.2885 mL | 0.7213 mL | |
| 80 mM | 0.0216 mL | 0.1082 mL | 0.2164 mL | 0.5410 mL | |
| 100 mM | 0.0173 mL | 0.0866 mL | 0.1731 mL | 0.4328 mL |
Mal-PEG8-Boc 関連分類
HY-133212 関連分類
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