MCL0020
Based on 1 Customer Validation
MCL0020 is a potent and selective melanocortin MC4 receptor antagonist, with an IC50 of 11.63 nM. MCL0020 dose-dependently and significantly attenuates restraint stress-induced anorexia without affecting food intake.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.93%
- CAS 番号: 475498-26-1
- 分子式: C34H39N7O4
- 分子量:609.72
-
保管条件:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
生物活性
-
化学情報
-
溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
-
Help & FAQs
-
HY-10624
THIQ
-
HY-148349
PF-07258669
-
HY-P0227
SHU 9119
-
HY-N2466
Melanotan I
-
HY-P1211
Adrenocorticotropic Hormone (ACTH) (1-39), human
-
![[D-Trp8]-γ-MSH](https://file.medchemexpress.com/product_pic/hy-p1217.gif)
HY-P1217
[D-Trp8]-γ-MSH
-
HY-P1531
γ-1-Melanocyte Stimulating Hormone (MSH), amide
-
HY-19870
Setmelanotide
-
HY-P1214
γ1-MSH
-
HY-P1213
JKC363
-
HY-P1208
PG-931
-
HY-107139
JNJ-10229570
生物活性
IC50: 11.63 (MC4)
MCL0020 inhibited [125I][N1e4, D-Phe7]α-MSH binding to membranes of COS-1 cells with IC50 values of 11.63[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 475498-26-1
-
性状 Solid
-
分子量 609.72
-
分子式 C34H39N7O4
-
Color White to off-white
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 125 mg/mL (205.01 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
-
データシート (272 KB)
-
SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
-
取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.6401 mL | 8.2005 mL | 16.4010 mL | 41.0024 mL |
| 5 mM | 0.3280 mL | 1.6401 mL | 3.2802 mL | 8.2005 mL | |
| 10 mM | 0.1640 mL | 0.8200 mL | 1.6401 mL | 4.1002 mL | |
| 15 mM | 0.1093 mL | 0.5467 mL | 1.0934 mL | 2.7335 mL | |
| 20 mM | 0.0820 mL | 0.4100 mL | 0.8200 mL | 2.0501 mL | |
| 25 mM | 0.0656 mL | 0.3280 mL | 0.6560 mL | 1.6401 mL | |
| 30 mM | 0.0547 mL | 0.2733 mL | 0.5467 mL | 1.3667 mL | |
| 40 mM | 0.0410 mL | 0.2050 mL | 0.4100 mL | 1.0251 mL | |
| 50 mM | 0.0328 mL | 0.1640 mL | 0.3280 mL | 0.8200 mL | |
| 60 mM | 0.0273 mL | 0.1367 mL | 0.2733 mL | 0.6834 mL | |
| 80 mM | 0.0205 mL | 0.1025 mL | 0.2050 mL | 0.5125 mL | |
| 100 mM | 0.0164 mL | 0.0820 mL | 0.1640 mL | 0.4100 mL |
MCL0020 関連分類
HY-107627 関連分類
Powered by Bioz