MDI-2268
Based on 1 Customer Validation
MDI-2268 is an inhibitor of plasma kallikrein inhibitor 1 (PAI-1). MDI-2268 has good antithrombotic properties and regulates blood coagulation and fibrinolysis process by enhancing fibrinolysis. MDI-2268 can be used in research areas such as deep vein thrombosis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.71%
- CAS 番号: 1609176-50-2
- 分子式: C10H10F3N3O3
- 分子量:277.20
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
MDI-2268 (1 mM, 3 days) prevents Paneth cell defects and apoptosis in Atg16l1 T300A organoids[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only. .
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Cell Line:Atg16l1 T300A organoids
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Concentration:1 mM
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Incubation Time:3 days
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Result:Reduced the cleaved caspase 3.
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:Mouse electrolytic IVC models[1]
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Dosage:1.5-3 mg/kg
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Administration:ip, every 8 hours for 6 doses
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Result:Reduced the thrombus weight.
化学情報
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CAS 番号 1609176-50-2
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性状 Solid
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分子量 277.20
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分子式 C10H10F3N3O3
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Color White to off-white
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SMILES
O=C(NN)C(NCC1=CC=CC(OC(F)(F)F)=C1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 166.67 mg/mL (601.26 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.6075 mL | 18.0375 mL | 36.0750 mL | 90.1876 mL |
| 5 mM | 0.7215 mL | 3.6075 mL | 7.2150 mL | 18.0375 mL | |
| 10 mM | 0.3608 mL | 1.8038 mL | 3.6075 mL | 9.0188 mL | |
| 15 mM | 0.2405 mL | 1.2025 mL | 2.4050 mL | 6.0125 mL | |
| 20 mM | 0.1804 mL | 0.9019 mL | 1.8038 mL | 4.5094 mL | |
| 25 mM | 0.1443 mL | 0.7215 mL | 1.4430 mL | 3.6075 mL | |
| 30 mM | 0.1203 mL | 0.6013 mL | 1.2025 mL | 3.0063 mL | |
| 40 mM | 0.0902 mL | 0.4509 mL | 0.9019 mL | 2.2547 mL | |
| 50 mM | 0.0722 mL | 0.3608 mL | 0.7215 mL | 1.8038 mL | |
| 60 mM | 0.0601 mL | 0.3006 mL | 0.6013 mL | 1.5031 mL | |
| 80 mM | 0.0451 mL | 0.2255 mL | 0.4509 mL | 1.1273 mL | |
| 100 mM | 0.0361 mL | 0.1804 mL | 0.3608 mL | 0.9019 mL |
MDI-2268 関連分類
HY-124577 関連分類
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