Metrizamide
Based on 1 Customer Validation
Metrizamide (Amipaque) is used as the contrast medium for angiography in neuroradiological investigations. Metrizamide inhibits human brain hexokinase.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.0%
- CAS 番号: 31112-62-6
- 分子式: C18H22I3N3O8
- 分子量:789.10
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
Metrizamide is a contrast medium possessing unique properties, one of which is that even in an isotonic solution it has a radiographic density sufficient for a diagnostic myelogram[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 31112-62-6
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性状 Solid
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分子量 789.10
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分子式 C18H22I3N3O8
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Color White to off-white
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SMILES
IC(C(N(C)C(C)=O)=C1I)=C(C(N[C@@H]2[C@@H](O)[C@H](O)[C@@H](CO)OC2O)=O)C(I)=C1NC(C)=O
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別名
Amipaque
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : ≥ 50 mg/mL (63.36 mM; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Vogelsang H, et al. Zerebrale und spinale Angiographie mit Metrizamid (Amipaque) [Cerebral and spinal angiography with metrizamide (amipaque) (author's transl)]. Rofo. 1978;129(5):559-561. [Content Brief]
[2]. Bertoni JM. Metrizamide inhibits human brain hexokinase. Neurology. 1982;32(8):884-887. [Content Brief]
[3]. Funkquist B. Myelographic localization of spinal cord compression in dogs. A comparison between cisternal and lumbar injections of metrizamide "Amipaque" in diagnosing and locating spinal cord compression. Acta Vet Scand. 1975;16(2):269-287. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.2673 mL | 6.3363 mL | 12.6727 mL | 31.6817 mL |
| 5 mM | 0.2535 mL | 1.2673 mL | 2.5345 mL | 6.3363 mL | |
| 10 mM | 0.1267 mL | 0.6336 mL | 1.2673 mL | 3.1682 mL | |
| 15 mM | 0.0845 mL | 0.4224 mL | 0.8448 mL | 2.1121 mL | |
| 20 mM | 0.0634 mL | 0.3168 mL | 0.6336 mL | 1.5841 mL | |
| 25 mM | 0.0507 mL | 0.2535 mL | 0.5069 mL | 1.2673 mL | |
| 30 mM | 0.0422 mL | 0.2112 mL | 0.4224 mL | 1.0561 mL | |
| 40 mM | 0.0317 mL | 0.1584 mL | 0.3168 mL | 0.7920 mL | |
| 50 mM | 0.0253 mL | 0.1267 mL | 0.2535 mL | 0.6336 mL | |
| 60 mM | 0.0211 mL | 0.1056 mL | 0.2112 mL | 0.5280 mL |