(-)-Codonopsine
(-)-Codonopsine is an alkaloid with antibacterial activity. (-)-Codonopsine can be used in research related to Staphylococcus aureus and Escherichia coli infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 26989-20-8
- 分子式: C14H21NO4
- 分子量:267.32
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
(-)-Codonopsine (0.5-1024 μg/mL; 18 h) inhibits Staphylococcus aureus (ATCC 29213) with a MIC of 32 μg/mL, Escherichia coli (ATCC 25922) with a MIC of 64 μg/mL[1].
(-)-Codonopsine (0.5-1024 μg/mL; 18 h) shows no activity (MIC >1024 μg/mL) against Klebsiella pneumoniae (ATCC 700603), Proteus mirabilis (ATCC 14153), Pseudomonas aeruginosa (ATCC 27853), Acinetobacter baumannii (clinical isolate), and Candida albicans (ATCC 10231)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 26989-20-8
-
分子量 267.32
-
分子式 C14H21NO4
-
SMILES
O[C@@H]1[C@H](N([C@@H]([C@H]1O)C)C)C2=CC(OC)=C(C=C2)OC
-
Structure Classification
-
Initial Source
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. El-Nezhawy AOH, et al. Design and total synthesis of (-)-codonopsinine, (-)-codonopsine and codonopsinine analogues by O-(2-oxopyrrolidin-5-yl)trichloroacetimidate as amidoalkylating agent with improved antimicrobial activity via solid lipid nanoparticle formulations. Bioorg Med Chem. 2019;27(7):1263-1273. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
- (-)-Codonopsine
- 26989-20-8
- Bacterial
- Proteus mirabilis (ATCC 14153)
- Staphylococcus aureus (ATCC 29213)
- solid lipid nanoparticle formulations
- Candida albicans
- bacterial infection
- Codonopsis clematidea
- Staphylococcus aureus
- Escherichia coli (ATCC 25922)
- Klebsiella pneumoniae (ATCC 700603)
- central nervous system
- Inhibitor
- inhibitor
- inhibit