Mito-Rh-S
Based on 1 Customer Validation
Mito-Rh-S is a ratiometric near-infrared (NIR) fluorescent probe that detects the fluctuation of mitochondrial HClO levels during ferroptosis in hepatocellular carcinoma (HCC).
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 97.03%
- 分子式: C40H39ClN2O8S
- 分子量:743.26
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保管条件:
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
Mito-Rh-S has an ultrafast response rate (2s) and large emission shift (115 nm). Mito-Rh-S has a high signal-to-noise ratio[1].
The cell experiments of Mito-Rh-S demonstrated that Fe2+- and Erastin-induced ferroptosis in HepG2 cells resulted in elevated levels of mitochondrial HClO[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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性状 Solid
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分子量 743.26
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分子式 C40H39ClN2O8S
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Color Blue to dark blue
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SMILES
O=Cl(=O)([O-])=O.CCN1C(C=CC=C2)=C2SC(C=C3/C=C4C5=[O+]C6=CC(N(CC)CC)=CC=C6C(C7=C(C(O)=O)C=CC=C7)=C5CCC/4)=C1C=C3OC
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
4°C, sealed storage, away from moisture
* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
溶剤 & 溶解度
DMSO : 20 mg/mL (26.91 mM; Need ultrasonic and warming; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (278 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.3454 mL | 6.7271 mL | 13.4542 mL | 33.6356 mL |
| 5 mM | 0.2691 mL | 1.3454 mL | 2.6908 mL | 6.7271 mL | |
| 10 mM | 0.1345 mL | 0.6727 mL | 1.3454 mL | 3.3636 mL | |
| 15 mM | 0.0897 mL | 0.4485 mL | 0.8969 mL | 2.2424 mL | |
| 20 mM | 0.0673 mL | 0.3364 mL | 0.6727 mL | 1.6818 mL | |
| 25 mM | 0.0538 mL | 0.2691 mL | 0.5382 mL | 1.3454 mL |
Mito-Rh-S 関連分類
HY-D2312 関連分類
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