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MK-2060

カスタマーレビュー

Based on 1 Customer Validation

MK-2060 is a monoclonal antibody factor XI inhibitor. MK-2060 binds to the A3 domain of coagulation factor XI (FXI), prevents FXIIa-mediated FXI activation, and blocks the binding/activation of FIX with FXIa, locking the zymogen in an inactive/non-activatable conformation, thereby prolonging aPTT. MK-2060 can be used in research on end-stage renal disease, ESRD requiring hemodialysis, and arteriovenous graft thrombosis.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度 : ≥99.0%
  • CAS 番号: 2812480-88-7
  • 分子量:145.33 kDa
  • 保管条件:
    Shipping with dry ice

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for MK-2060
  • MK-2060 Chemical Structure
    MK-2060 構造式
CAS 番号: 2812480-88-7
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Immobilized Human Factor XI Protein, His Tag can bind MK-2060. The EC50 for this effect is 59.5 ng/mL.

  • MK-2060 Chemical Structure
    1/16
  • MK-2060
  • Immobilized Human Factor XI Protein, His Tag can bind MK-2060. The EC50 for this effect is 59.5 ng/mL.