ML-10
Based on 1 Customer Validation
ML-10 is a small molecule apoptosis probe. Due to the presence of fluorine atoms, ML-10 can be radiolabeled with 18F isotopes and can be used for apoptosis positron emission tomography imaging studies. ML-10 is selectively taken up and accumulated in apoptotic cells, while being excluded from live or necrotic cells. In addition, the uptake of ML-10 is associated with apoptotic features such as caspase activation, Annexin-V binding, and disruption of mitochondrial membrane potential.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 95.0%
- CAS 番号: 1216897-16-3
- 分子式: C9H15FO4
- 分子量:206.21
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
臨床実験
| NCT Number | Sponsor | Condition | Start Date |
Phase
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|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 1216897-16-3
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性状 Solid
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分子量 206.21
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分子式 C9H15FO4
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Color White to off-white
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SMILES
O=C(O)C(C)(CCCCCF)C(O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
DMSO : 100 mg/mL (484.94 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.8494 mL | 24.2471 mL | 48.4943 mL | 121.2356 mL |
| 5 mM | 0.9699 mL | 4.8494 mL | 9.6989 mL | 24.2471 mL | |
| 10 mM | 0.4849 mL | 2.4247 mL | 4.8494 mL | 12.1236 mL | |
| 15 mM | 0.3233 mL | 1.6165 mL | 3.2330 mL | 8.0824 mL | |
| 20 mM | 0.2425 mL | 1.2124 mL | 2.4247 mL | 6.0618 mL | |
| 25 mM | 0.1940 mL | 0.9699 mL | 1.9398 mL | 4.8494 mL | |
| 30 mM | 0.1616 mL | 0.8082 mL | 1.6165 mL | 4.0412 mL | |
| 40 mM | 0.1212 mL | 0.6062 mL | 1.2124 mL | 3.0309 mL | |
| 50 mM | 0.0970 mL | 0.4849 mL | 0.9699 mL | 2.4247 mL | |
| 60 mM | 0.0808 mL | 0.4041 mL | 0.8082 mL | 2.0206 mL | |
| 80 mM | 0.0606 mL | 0.3031 mL | 0.6062 mL | 1.5154 mL | |
| 100 mM | 0.0485 mL | 0.2425 mL | 0.4849 mL | 1.2124 mL |
ML-10 関連分類
HY-76573 関連分類
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