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United States

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製品番号: HY-N16831

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Moracenin D

Moracenin D is a natural flavonoid.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 78277-79-9
分子式: C₄₀H₃₈O₁₂
分子量:710.72

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (275 KB)

Moracenin D 構造式

CAS 番号: 78277-79-9

価格（税別）

Amount: USD 0.00

* アイテムを追加する前、数量をご選択ください

Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

Moracenin D is a natural flavonoid.

IC₅₀ & Target

^[1]

Nurr1/NR4A2

α-synuclein

体外実験

Moracenin D (0.16-4 μM; 24 h) protects SH-SY5Y cells against dopamine-induced cell death (EC₅₀ = 3.6 μM)^[1].
Moracenin D (0.16-4 μM; 9-15 h) up-regulates nurr1 expression and down-regulates α-synuclein expression in dopamine-treated cells in a dose-dependent manner^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Cell Viability Assay^[1]

Cell Line:

human neuroblastoma SH-SY5Y cells
Concentration:

0.16-4 μM
Incubation Time:

24 h
Result:

Protected SH-SY5Y cells against dopamine-induced cell death with an EC₅₀ of 3.6 ± 0.9 μM

RT-PCR^[1]

Cell Line:

human neuroblastoma SH-SY5Y cells
Concentration:

0.16-4 μM
Incubation Time:

9 h
Result:

Up-regulated nurr1 mRNA expression and down-regulated α-synuclein mRNA expression in a dose-dependent manner compared to the dopamine-alone group

Western Blot Analysis^[1]

Cell Line:

human neuroblastoma SH-SY5Y cells
Concentration:

0.16-4 μM
Incubation Time:

15 h
Result:

Increased nurr1 protein expression and decreased α-synuclein protein expression in a dose-dependent manner compared to the dopamine-alone group

化学情報

CAS 番号 78277-79-9
分子量 710.72
分子式 C₄₀H₃₈O₁₂
SMILES

OC1=CC(O)=C(C(C(CCC(C)(O)C)=C(C2=C(C=C(C=C2)O)O)O3)=O)C3=C1[C@@H]4[C@H]([C@H](C5=C(C=C(C=C5)O)O)CC(C)=C4)C(C6=C(C=C(C=C6)O)O)=O
Structure Classification
- Flavonoids
- Flavones
- Phenols
- Polyphenols
Initial Source
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

バッチを選択:

純度: 99.98%

Assay: 99.98%

ee.: 99.98%

データシート (275 KB)
COA (2659 KB)
元素分析報告書 (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
取扱説明書 (2659 KB)

参考文献

[1]. Ham A, et al. Moracenin D from Mori Cortex radicis protects SH-SY5Y cells against dopamine-induced cell death by regulating nurr1 and α-synuclein expression. Phytother Res. 2012;26(4):620-624. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Keywords

MOQ

Minimum order quantity

100 mg

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