Mtb-IN-8
Mtb-IN-8 (compound 5jb) is an orally active inhibitor of Mycobacterium tuberculosis (Mtb) with MIC values of 0.03 μg/mL for H37Rv and 0.125-0.06 μg/mL for MDR-Mtb, respectively.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2549199-96-2
- 分子式: C17H18N4O5S
- 分子量:390.41
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HK-2 | IC50 |
41.11 μg/mL
Compound: 5jb
|
Cytotoxicity against HK-2 cells incubated for 48 hrs by CCK8 assay
Cytotoxicity against HK-2 cells incubated for 48 hrs by CCK8 assay
|
[PMID: 39166949] |
| Vero | IC50 |
>64 μg/mL
Compound: 5jb
|
Cytotoxicity against african green monkey Vero cells incubated for 48 hrs by CCK8 assay
Cytotoxicity against african green monkey Vero cells incubated for 48 hrs by CCK8 assay
|
[PMID: 39166949] |
化学情報
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CAS 番号 2549199-96-2
-
分子量 390.41
-
分子式 C17H18N4O5S
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SMILES
COC1=CC=C([C@@H]2C(C(NC(SCCC)=N3)=O)=C3NC(C2)=O)C([N+]([O-])=O)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)