N3-CMC
N3-CMC is a click chemistry reagent. N3-CMC containing an azide group can undergo ring strain-promoted alkyne-azide cycloaddition (SPAAC) with molecules containing DBCO or BCN groups. N3-CMC can also undergo copper-catalyzed azide-alkyne cycloaddition (CuAAc) with molecules containing alkyne groups. N3-CMC reacts specifically with the pseudouridine (Ψ)-containing RNA, and biotin is subsequently conjugated to the N3-CMC-Ψ RNA via click chemistry, quantitatively analyzing the dynamic changes of Ψ.
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- CAS 番号: 1801187-61-0
- 分子式: C21H32N6O4S
- 分子量:464.58
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
製品説明
体外実験
Click chemistry is used to describe the selective, modular, wide range and high-yield chemical reactions that allow rapid synthesis of new compounds through heteroatom linking (C-X-C). Bertozzi developed click chemistry in a new dimension—Bioorthogonal chemistry. It is defined as a rapid and selective reaction that does not interfere with biological processes under physiological conditions. Common reaction structures of click chemistry, such as Azide, Alkyne, DBCO, BCN, TCO and Tetrazine.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 1801187-61-0
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分子量 464.58
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分子式 C21H32N6O4S
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SMILES
C[N+]1(CCN=[C@@]=N[C@H]2CC[C@@H](N=[N+]=[N-])CC2)CCOCC1.O=S(C3=CC=C(C)C=C3)([O-])=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)