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Nirsevimab

(別名: MEDI8897)
2 Cited Publications
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Based on 2 publication(s) in Google Scholar

Nirsevimab (MEDI8897) is a recombinant monoclonal antibody against human respiratory syncytial virus (RSV). Nirsevimab has neutralizing activity against RSV A and RSV B viruses, with IC50 values of 5.42 ng/mL and 9.71 ng/mL, respectively. Nirsevimab can be used for research on respiratory infections.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 純度: 98.63%
  • CAS 番号: 1989556-22-0
  • 分子量:146.31 kDa
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Nirsevimab
  • Experimental Validation Results for Nirsevimab
  • Experimental Validation Results for Nirsevimab
  • Experimental Validation Results for Nirsevimab
  • Nirsevimab Chemical Structure
    Nirsevimab 構造式
CAS 番号: 1989556-22-0
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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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MedChemExpress（MCE）の使用を引用している文献 Nirsevimab

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  • Bio/Physico-chemical Assay
  • Bio/Physico-chemical Assay

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Assay Types
  • 1/16

    Human IgG1 kappa

  • 1/16

    Immobilized Fusion glycoprotein F0/F Protein, HRSV (sf9, His, HY-P75182) can bind Nirsevimab. The EC50 for this effect is 44 ng/mL.

  • 1/16

    Nirsevimab purchased from MedChemExpress. Usage Cited in: bioRxiv. 2026 Feb 4.

    Customer Validation
     All MARMs could be rescued by at least one other mAb. Three RSM01 MARMs (RSM-1 to RSM-3) could still be neutralised by nirsevimab and clesrovimab.

  • 1/16

    Nirsevimab purchased from MedChemExpress. Usage Cited in: bioRxiv. 2026 Feb 4.

    Customer Validation
     RSV-B isolates displayed 17 highly variable positions, two of which are located in overlapping RSM01/nirsevimab binding sites.

  • Nirsevimab Chemical Structure
    1/16
  • Nirsevimab
  • Immobilized Fusion glycoprotein F0/F Protein, HRSV (sf9, His, HY-P75182) can bind Nirsevimab. The EC50 for this effect is 44 ng/mL.