nor-MC3
Based on 1 Customer Validation
nor-MC3 is an MC3-type ionizable lipid with C17 unsaturated chains, formulated in lipid nanoparticles for nucleic acid (mRNA and siRNA) delivery and supports in vitro and in vivo transfection.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2870681-06-2
- 分子式: C41H75NO2
- 分子量:614.04
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保管条件:
Solution, -20°C, 2 years
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- プロトコル
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
nor-MC3-based siRNA LNPs (0.03-1 μg/mL siRNA) exhibit comparable in vitro knockdown efficiency in stably luciferase-expressing 22Rv1 cells to MC3-based LNPs, with enhanced activity at 0.5 μg/mL siRNA and a similar EC50 value of 0.1644 μg/mL siRNA[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
体内実験
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:C57BL/6J (6-8 weeks old)[1]
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Dosage:1 mg/kg mRNA
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Administration:i.v.; single injection
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Result:Exhibited high luminescence intensity per mg liver or spleen tissue.
化学情報
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CAS 番号 2870681-06-2
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性状 Liquid
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分子量 614.04
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分子式 C41H75NO2
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SMILES
CN(C)CCCC(OC(CCCCCCC/C=C\C/C=C\CCCCC)CCCCCCC/C=C\C/C=C\CCCCC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Solution, -20°C, 2 years
溶剤 & 溶解度
体外:
Ethanol : 25 mg/mL (40.71 mM; Need ultrasonic and warming)
純度とドキュメンテーション
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データシート (267 KB)
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SDS (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| Ethanol | 1 mM | 1.6286 mL | 8.1428 mL | 16.2856 mL | 40.7140 mL |
| 5 mM | 0.3257 mL | 1.6286 mL | 3.2571 mL | 8.1428 mL | |
| 10 mM | 0.1629 mL | 0.8143 mL | 1.6286 mL | 4.0714 mL | |
| 15 mM | 0.1086 mL | 0.5429 mL | 1.0857 mL | 2.7143 mL | |
| 20 mM | 0.0814 mL | 0.4071 mL | 0.8143 mL | 2.0357 mL | |
| 25 mM | 0.0651 mL | 0.3257 mL | 0.6514 mL | 1.6286 mL | |
| 30 mM | 0.0543 mL | 0.2714 mL | 0.5429 mL | 1.3571 mL | |
| 40 mM | 0.0407 mL | 0.2036 mL | 0.4071 mL | 1.0178 mL |
nor-MC3 関連分類
HY-185010 関連分類
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