NS2359
NS2359 (GSK372475) is a serotonin-norepinephrine-dopamine triple reuptake inhibitor. NS2359 is used for research on depression.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 195875-68-4
- 分子式: C16H21Cl2NO
- 分子量:314.25
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
NS2359 simultaneously blocks three monoamine transporters and increases the levels of three types of neurotransmitters in the synaptic cleft to regulate mood, cognition and reward pathways.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
CAS 番号 195875-68-4
-
分子量 314.25
-
分子式 C16H21Cl2NO
-
SMILES
COC[C@@H]1[C@@H](C2=CC(Cl)=C(C=C2)Cl)C[C@@]3([H])N([C@]1([H])CC3)C
-
別名
GSK372475
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Learned S, et al. Efficacy, safety, and tolerability of a triple reuptake inhibitor GSK372475 in the treatment of patients with major depressive disorder: two randomized, placebo- and active-controlled clinical trials. Journal of psychopharmacology (Oxford, England). 2012 May;26(5):653-62. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)