Perlolyrin
Based on 1 Customer Validation
Perlolyrin (Tribulusterine) is an alkaloid that can be isolated from dried fruits of Tribulus terrestris.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.81%
- CAS 番号: 29700-20-7
- 分子式: C16H12N2O2
- 分子量:264.28
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Neutrophil | IC50 |
0.45 μg/mL
Compound: 43
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Anti-inflammatory activity in human neutrophils assessed as inhibition of FMLP/CB-induced superoxide anion generation
Anti-inflammatory activity in human neutrophils assessed as inhibition of FMLP/CB-induced superoxide anion generation
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[PMID: 21848266] |
| Neutrophil | IC50 |
1.68 μg/mL
Compound: 43
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Anti-inflammatory activity in human neutrophils assessed as inhibition of FMLP/CB-induced elastase release
Anti-inflammatory activity in human neutrophils assessed as inhibition of FMLP/CB-induced elastase release
|
[PMID: 21848266] |
| RAW264.7 | IC50 |
8.7 μM
Compound: 15
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Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced NO production pretreated for 30 mins followed by LPS stimulation for 24 hrs by Griess assay
Antiinflammatory activity in mouse RAW264.7 cells assessed as reduction in LPS-induced NO production pretreated for 30 mins followed by LPS stimulation for 24 hrs by Griess assay
|
[PMID: 28499733] |
化学情報
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CAS 番号 29700-20-7
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性状 Solid
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分子量 264.28
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分子式 C16H12N2O2
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Color Light yellow to yellow
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SMILES
OCC1=CC=C(O1)C2=NC=CC3=C2NC4=C3C=CC=C4
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別名
Tribulusterine
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (378.39 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.7839 mL | 18.9193 mL | 37.8387 mL | 94.5966 mL |
| 5 mM | 0.7568 mL | 3.7839 mL | 7.5677 mL | 18.9193 mL | |
| 10 mM | 0.3784 mL | 1.8919 mL | 3.7839 mL | 9.4597 mL | |
| 15 mM | 0.2523 mL | 1.2613 mL | 2.5226 mL | 6.3064 mL | |
| 20 mM | 0.1892 mL | 0.9460 mL | 1.8919 mL | 4.7298 mL | |
| 25 mM | 0.1514 mL | 0.7568 mL | 1.5135 mL | 3.7839 mL | |
| 30 mM | 0.1261 mL | 0.6306 mL | 1.2613 mL | 3.1532 mL | |
| 40 mM | 0.0946 mL | 0.4730 mL | 0.9460 mL | 2.3649 mL | |
| 50 mM | 0.0757 mL | 0.3784 mL | 0.7568 mL | 1.8919 mL | |
| 60 mM | 0.0631 mL | 0.3153 mL | 0.6306 mL | 1.5766 mL | |
| 80 mM | 0.0473 mL | 0.2365 mL | 0.4730 mL | 1.1825 mL | |
| 100 mM | 0.0378 mL | 0.1892 mL | 0.3784 mL | 0.9460 mL |