Boc-NH-PEG3
Based on 1 Customer Validation
Boc-NH-PEG3 (PROTAC Linker 10) is a PEG-based PROTAC linker can be used in the synthesis of PROTACs.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.0%
- CAS 番号: 139115-92-7
- 分子式: C11H23NO5
- 分子量:249.30
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保管条件:Pure form -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
PROTAC Linkers アイソフォーム固有の製品をすべて表示
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生物活性
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PEGs |
PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 139115-92-7
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性状 Liquid (Density: 1.071±0.06 g/cm3)
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分子量 249.30
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分子式 C11H23NO5
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Color Colorless to light yellow
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SMILES
O=C(OC(C)(C)C)NCCOCCOCCO
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別名
PROTAC Linker 10
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Pure form -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (401.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (266 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.0112 mL | 20.0562 mL | 40.1123 mL | 100.2808 mL |
| 5 mM | 0.8022 mL | 4.0112 mL | 8.0225 mL | 20.0562 mL | |
| 10 mM | 0.4011 mL | 2.0056 mL | 4.0112 mL | 10.0281 mL | |
| 15 mM | 0.2674 mL | 1.3371 mL | 2.6742 mL | 6.6854 mL | |
| 20 mM | 0.2006 mL | 1.0028 mL | 2.0056 mL | 5.0140 mL | |
| 25 mM | 0.1604 mL | 0.8022 mL | 1.6045 mL | 4.0112 mL | |
| 30 mM | 0.1337 mL | 0.6685 mL | 1.3371 mL | 3.3427 mL | |
| 40 mM | 0.1003 mL | 0.5014 mL | 1.0028 mL | 2.5070 mL | |
| 50 mM | 0.0802 mL | 0.4011 mL | 0.8022 mL | 2.0056 mL | |
| 60 mM | 0.0669 mL | 0.3343 mL | 0.6685 mL | 1.6713 mL | |
| 80 mM | 0.0501 mL | 0.2507 mL | 0.5014 mL | 1.2535 mL | |
| 100 mM | 0.0401 mL | 0.2006 mL | 0.4011 mL | 1.0028 mL |