(R)-Octopamine
Based on 1 Customer Validation
(R)-Octopamine is a Gs-coupled receptor agonist. (R)-Octopamine binds to the orthosteric site of BmOAR2 and interacts with the Asp115, Ser202 and Tyr300 residues to activate the receptor, which couples to Gs protein and thereby stimulates adenylate cyclase activity.
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- 純度: 95.22%
- CAS 番号: 876-04-0
- 分子式: C8H11NO2
- 分子量:153.18
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Adrenergic Receptor アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
体外実験
(R)-Octopamine (0.1 nM-10 μM; 20 min after IBMX preincubation) potently activates wild-type BmOAR2 in HEK-293 cells to elevate intracellular cAMP levels, with an EC50 of approximately 1.0 nM and maximum response at 10 nM[1].
(R)-Octopamine interacts with BmOAR2 via hydrogen bonds between its phenolic OH group and Ser202/Tyr300, and between its NH2/β-OH groups and Asp115[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 876-04-0
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性状 Solid
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分子量 153.18
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分子式 C8H11NO2
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Color White to light yellow
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SMILES
NC[C@@H](C1=CC=C(C=C1)O)O
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Structure Classification
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Initial Source
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
純度とドキュメンテーション
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データシート (266 KB)
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SDS (393 KB)
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- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
(R)-Octopamine 関連分類
HY-N11141 関連分類
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