(Rac)-DIOA
(Rac)-DIOA ((Rac)-[(Dihydroindenyl) oxy]acetic acid) is the racemate of DIOA (HY-137148), which inhibits acid-sensitive outwardly rectifying (ASOR) and volume-sensitive outwardly rectifying (VSOR) anion channel currents, and classically inhibits K+-Cl- cotransporters (KCC). (Rac)-DIOA can be used to study mechanisms related to ischemic cerebrovascular disease, neurological diseases, tumor acidosis microenvironment, and cell volume disorders.
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- CAS 番号: 81166-34-9
- 分子式: C20H24Cl2O4
- 分子量:399.31
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
化学情報
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CAS 番号 81166-34-9
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分子量 399.31
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分子式 C20H24Cl2O4
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SMILES
O=C(COC1=C(Cl)C(Cl)=C(C(C(CCCC)(C2CCCC2)C3)=O)C3=C1)O
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別名
(Rac)-[(Dihydroindenyl)oxy]acetic acid
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
[1]. Sato-Numata K, et al. Distinct pharmacological and molecular properties of the acid-sensitive outwardly rectifying (ASOR) anion channel from those of the volume-sensitive outwardly rectifying (VSOR) anion channel. Pflugers Archiv : European journal of physiology. 2016 May;468(5):795-803. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
(Rac)-DIOA 関連分類
HY-137148A 関連分類
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