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製品番号: HY-184093

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Rexaceract

(別名: Rexaceractum)

Rexaceract (Rexaceractum) is a heteroaryl compound that binds to β-glucocerebrosidase. Rexaceract maintains the conformational stability of β-glucocerebrosidase and exhibits activating activity. Rexaceract can be used in the research of nervous system-related diseases such as neurodegenerative diseases with Parkinsonism, epilepsy, and schizophrenia.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
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CAS 番号: 2648407-86-5
分子式: C₂₁H₁₉FN₄O
分子量:362.40

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Rexaceract 構造式

CAS 番号: 2648407-86-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

Rexaceract (Example 71) (6-50 μM; 4-day incubation) binds allosterically to β-glucocerebrosidase in human fibroblasts carrying the L444P mutation, increasing the enzyme activity by 1.2- to 1.7-fold^[1].\n

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 2648407-86-5
分子量 362.40
分子式 C₂₁H₁₉FN₄O
SMILES

O=C(C1=NC(NC2=C(F)C=CC=C2)=CC(N)=C1)NC3CC4=C(C3)C=CC=C4
別名

Rexaceractum
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Collazo AMG, et al. Heteroaryl compounds and therapeutic uses thereof in conditions associated with the alteration of the activity of beta-glucocerebrosidase. WO2021105908A1. WIPO; 2021 Jun 3.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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希釈計算機

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

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100 mg

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