Ritalinic acid
Based on 1 Customer Validation
Ritalinic acid (Ritalinate) is a metabolite of Methylphenidate. Ritalinic acid has no biological activity or only extremely low biological activity. The concentration of Ritalinic acid detected in university campus sewage shows a gradual upward trend in the first semester, while no obvious periodic variation pattern related to academic stress is observed in the second semester. Ritalinic acid can be used in studies related to attention deficit disorder, narcolepsy, depression and attention deficit hyperactivity disorder.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度 : 99.81%
- CAS 番号: 19395-41-6
- 分子式: C13H17NO2
- 分子量:219.28
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
製品説明
体外実験
化学情報
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CAS 番号 19395-41-6
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性状 Solid
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分子量 219.28
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分子式 C13H17NO2
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Color White to off-white
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SMILES
C2=C(C(C1CCCCN1)C(O)=O)C=CC=C2
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別名
Ritalinic acid; Ritalinate
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
体外:
1 M NaOH : ≥ 100 mg/mL (456.04 mM)
H2O : 4.03 mg/mL (18.38 mM; ultrasonic and adjust pH to 12 with 1 M NaOH)
* "≥" means soluble, but saturation unknown.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (276 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Markowitz JS, et al. Ethylphenidate formation in human subjects after the administration of a single dose of methylphenidate and ethanol. Drug Metab Dispos. 2000;28(6):620-624. [Content Brief]
[2]. del Mar Ramirez Fernandez M, et al. Liquid chromatography-tandem mass spectrometry method for the simultaneous analysis of multiple hallucinogens, chlorpheniramine, ketamine, ritalinic acid, and metabolites, in urine. J Anal Toxicol. 2007;31(8):497-504. [Content Brief]
[3]. Letzel M, et al. Occurrence and fate of the human pharmaceutical metabolite ritalinic acid in the aquatic system. Chemosphere. 2010;81(11):1416-1422. [Content Brief]
[4]. Burgard DA, et al. Potential trends in Attention Deficit Hyperactivity Disorder (ADHD) drug use on a college campus: wastewater analysis of amphetamine and ritalinic acid. Sci Total Environ. 2013;450-451:242-249. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O / 1 M NaOH | 1 mM | 4.5604 mL | 22.8019 mL | 45.6038 mL | 114.0095 mL |
| 5 mM | 0.9121 mL | 4.5604 mL | 9.1208 mL | 22.8019 mL | |
| 10 mM | 0.4560 mL | 2.2802 mL | 4.5604 mL | 11.4009 mL | |
| 15 mM | 0.3040 mL | 1.5201 mL | 3.0403 mL | 7.6006 mL | |
| 1 M NaOH | 20 mM | 0.2280 mL | 1.1401 mL | 2.2802 mL | 5.7005 mL |
| 25 mM | 0.1824 mL | 0.9121 mL | 1.8242 mL | 4.5604 mL | |
| 30 mM | 0.1520 mL | 0.7601 mL | 1.5201 mL | 3.8003 mL | |
| 40 mM | 0.1140 mL | 0.5700 mL | 1.1401 mL | 2.8502 mL | |
| 50 mM | 0.0912 mL | 0.4560 mL | 0.9121 mL | 2.2802 mL | |
| 60 mM | 0.0760 mL | 0.3800 mL | 0.7601 mL | 1.9002 mL | |
| 80 mM | 0.0570 mL | 0.2850 mL | 0.5700 mL | 1.4251 mL | |
| 100 mM | 0.0456 mL | 0.2280 mL | 0.4560 mL | 1.1401 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Ritalinic acid 関連分類
HY-W042214 関連分類
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Keywords
- Ritalinic acid
- 19395-41-6
- Ritalinate
- Drug Metabolite
- Environmental Pollutants
- adult human urine
- college campus wastewater
- attention-deficit disorder
- activated sludge sewage treatment systems
- humans
- depression
- sludge microorganisms
- narcolepsy
- childhood hyperkinesis
- municipal wastewater treatment plant
- Inhibitor
- inhibitor
- inhibit