(S)-Tersolisib
Based on 1 Customer Validation
(S)-STX-478 is the S-enantiomer of STX-478. STX-478 is a selective inhibitor of PI3Kα mutants, preventing metabolic dysfunction and demonstrating antitumor activity in xenograft mouse models with PI3Kα mutant tumors.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.18%
- CAS 番号: 2883540-91-6
- 分子式: C16H12F5N5O2
- 分子量:401.29
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
化学情報
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CAS 番号 2883540-91-6
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性状 Solid
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分子量 401.29
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分子式 C16H12F5N5O2
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Color White to off-white
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SMILES
NC1=NC=C(C=N1)NC(N[C@@H](C2=C(C3=CC(F)=CC(F)=C3O2)C)C(F)(F)F)=O
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別名
(S)-STX-478; (S)-STX-478-101; (S)-LY4064809
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (249.20 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.4920 mL | 12.4598 mL | 24.9196 mL | 62.2991 mL |
| 5 mM | 0.4984 mL | 2.4920 mL | 4.9839 mL | 12.4598 mL | |
| 10 mM | 0.2492 mL | 1.2460 mL | 2.4920 mL | 6.2299 mL | |
| 15 mM | 0.1661 mL | 0.8307 mL | 1.6613 mL | 4.1533 mL | |
| 20 mM | 0.1246 mL | 0.6230 mL | 1.2460 mL | 3.1150 mL | |
| 25 mM | 0.0997 mL | 0.4984 mL | 0.9968 mL | 2.4920 mL | |
| 30 mM | 0.0831 mL | 0.4153 mL | 0.8307 mL | 2.0766 mL | |
| 40 mM | 0.0623 mL | 0.3115 mL | 0.6230 mL | 1.5575 mL | |
| 50 mM | 0.0498 mL | 0.2492 mL | 0.4984 mL | 1.2460 mL | |
| 60 mM | 0.0415 mL | 0.2077 mL | 0.4153 mL | 1.0383 mL | |
| 80 mM | 0.0311 mL | 0.1557 mL | 0.3115 mL | 0.7787 mL | |
| 100 mM | 0.0249 mL | 0.1246 mL | 0.2492 mL | 0.6230 mL |