(S)-Subasumstat
Based on 1 Customer Validation
(S)-Subasumstat is the isomer of Subasumstat (HY-111789). Subasumstat (TAK-981) is a first in class and selective inhibitor of the SUMOylation enzymatic cascade, with potential immune-activating and antineoplastic activities.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.39%
- CAS 番号: 1858282-76-4
- 分子式: C25H28ClN5O5S2
- 分子量:578.10
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
生物活性
化学情報
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CAS 番号 1858282-76-4
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性状 Solid
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分子量 578.10
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分子式 C25H28ClN5O5S2
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Color White to light yellow
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SMILES
O=S(OC[C@@H]1[C@@H](O)C[C@H](NC2=NC=NC=C2C(C3=CC([C@H]4NCCC5=C4C=C(Cl)C=C5)=C(C)S3)=O)C1)(N)=O
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別名
(S)-TAK-981
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (172.98 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (272 KB)
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SDS (254 KB)
- English - EN (254 KB)
- Français - FR (254 KB)
- Deutsch - DE (254 KB)
- Norwegian - NO (254 KB)
- Español - ES (254 KB)
- Swedish - SV (254 KB)
- Italian - IT (254 KB)
- Korean - KR (254 KB)
- Portuguese - PT (254 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Sumoylation inhibitor TAK-981.
[2]. TAK-981.
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.7298 mL | 8.6490 mL | 17.2980 mL | 43.2451 mL |
| 5 mM | 0.3460 mL | 1.7298 mL | 3.4596 mL | 8.6490 mL | |
| 10 mM | 0.1730 mL | 0.8649 mL | 1.7298 mL | 4.3245 mL | |
| 15 mM | 0.1153 mL | 0.5766 mL | 1.1532 mL | 2.8830 mL | |
| 20 mM | 0.0865 mL | 0.4325 mL | 0.8649 mL | 2.1623 mL | |
| 25 mM | 0.0692 mL | 0.3460 mL | 0.6919 mL | 1.7298 mL | |
| 30 mM | 0.0577 mL | 0.2883 mL | 0.5766 mL | 1.4415 mL | |
| 40 mM | 0.0432 mL | 0.2162 mL | 0.4325 mL | 1.0811 mL | |
| 50 mM | 0.0346 mL | 0.1730 mL | 0.3460 mL | 0.8649 mL | |
| 60 mM | 0.0288 mL | 0.1442 mL | 0.2883 mL | 0.7208 mL | |
| 80 mM | 0.0216 mL | 0.1081 mL | 0.2162 mL | 0.5406 mL | |
| 100 mM | 0.0173 mL | 0.0865 mL | 0.1730 mL | 0.4325 mL |