SA1103064
SA1103064 is a potent antibiotic with antibacterial activity against multiple resistant bacterial strains. SA1103064 binds to the bacterial ribosome's nascent peptide exit tunnel. SA1103064 can be used for the research of bacterial infections.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C39H50FN7O6
- 分子量:731.86
-
保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Antibiotic アイソフォーム固有の製品をすべて表示
More
生物活性
製品説明
体外実験
SA1103064 (compound 48a) binds to the E. coli ribosome's nascent peptide exit tunnel, forming π-stacking interactions with U1782-U2586 and van der Waals interactions with U2585, occupying the site of tetracenomycin X and mimicking VS1 binding contacts[1].
SA1103064 exhibits potent antibacterial activity against multiple Gram-positive strains, including drug-resistant isolates, with MIC values ranging from 1 to 8 μg/mL[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
-
分子量 731.86
-
分子式 C39H50FN7O6
-
SMILES
[H][C@]12CCCN1C(C3=COC(C[C@@H](C[C@@H](/C=C(/C=C/CNC(/C=C/[C@H]([C@H](OC2=O)C(C)C)CCCCCN4C=C(N=N4)C5=CC=NC=C5)=O)C)O)F)=N3)=O
-
輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
Keywords
- SA1103064
- SA 1103064
- SA-1103064
- Antibiotic
- Bacterial
- VatA/Vgb-resistant Staphylococcus aureus
- U2585
- bacterial infections
- Gram-positive strains
- bacterial ribosome
- U1782-U2586
- nascent peptide exit tunnel
- multidrug-resistant bacterial infections
- E. coli ribosome
- ErmC-resistant Staphylococcus aureus
- Inhibitor
- inhibitor
- inhibit