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SB-209670

SB-209670 is an extremely potent and highly specific non-peptide, subnanomolar endothelin (ET) receptor antagonist. SB 209670 selectively inhibits binding of 125I-labeled ET-1 to cloned human ET receptor subtypes ETA and ETB (Ki=0.2 and 18 nM, respectively). SB 209670 produces a dose-dependent reduction in blood pressure in hypertensive rats, protects from ischemia-induced neuronal degeneration in a gerbil stroke model, and attenuates neointima formation following rat carotid artery balloon angioplasty.

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  • CAS 番号: 157659-79-5
  • 分子式: C29H28O9
  • 分子量:520.53
  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • SB-209670 Chemical Structure
    SB-209670 構造式
CAS 番号: 157659-79-5
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    SB-209670 Chemical Structure
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