SPP-DM1
Based on 1 Customer Validation
SPP-DM1 is a agent-linker conjugate for ADC with potent antitumor activity by using DM1 (a potent microtubule-disrupting agent), linked via the ADC linker SPP.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 96.29%
- CAS 番号: 452072-20-7
- 分子式: C44H59ClN4O14S2
- 分子量:967.54
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保管条件:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
Drug-Linker Conjugates for ADC アイソフォーム固有の製品をすべて表示
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生物活性
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Maytansinoids |
化学情報
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CAS 番号 452072-20-7
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性状 Solid
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分子量 967.54
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分子式 C44H59ClN4O14S2
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Color White to off-white
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SMILES
C[C@]12[C@H]([C@@H]([C@](O3)([H])C[C@]([C@](/C=C/C=C(C)/CC4=CC(N(C)C(C[C@]2([H])OC([C@H](C)N(C)C(CCSSC(C)CCC(ON5C(CCC5=O)=O)=O)=O)=O)=O)=C(C(OC)=C4)Cl)([H])OC)(NC3=O)O)C)O1
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 100 mg/mL (103.35 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (273 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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取扱説明書 (2659 KB)
参考文献
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 1.0335 mL | 5.1677 mL | 10.3355 mL | 25.8387 mL |
| 5 mM | 0.2067 mL | 1.0335 mL | 2.0671 mL | 5.1677 mL | |
| 10 mM | 0.1034 mL | 0.5168 mL | 1.0335 mL | 2.5839 mL | |
| 15 mM | 0.0689 mL | 0.3445 mL | 0.6890 mL | 1.7226 mL | |
| 20 mM | 0.0517 mL | 0.2584 mL | 0.5168 mL | 1.2919 mL | |
| 25 mM | 0.0413 mL | 0.2067 mL | 0.4134 mL | 1.0335 mL | |
| 30 mM | 0.0345 mL | 0.1723 mL | 0.3445 mL | 0.8613 mL | |
| 40 mM | 0.0258 mL | 0.1292 mL | 0.2584 mL | 0.6460 mL | |
| 50 mM | 0.0207 mL | 0.1034 mL | 0.2067 mL | 0.5168 mL | |
| 60 mM | 0.0172 mL | 0.0861 mL | 0.1723 mL | 0.4306 mL | |
| 80 mM | 0.0129 mL | 0.0646 mL | 0.1292 mL | 0.3230 mL | |
| 100 mM | 0.0103 mL | 0.0517 mL | 0.1034 mL | 0.2584 mL |
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