ST8154AA1
ST8154AA1 is a part of antibody agent conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity.
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- CAS 番号: 2247025-59-6
- 分子式: C36H51N5O8S
- 分子量:713.88
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
Drug-Linker Conjugates for ADC アイソフォーム固有の製品をすべて表示
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生物活性
製品説明
IC50 & Target
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Traditional Cytotoxic Agents |
化学情報
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CAS 番号 2247025-59-6
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分子量 713.88
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分子式 C36H51N5O8S
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SMILES
OC([C@H]1CC[C@H](CNC(CCCCCN2C(CC(SCCCCC[C@H](NC([C@H]3CCC(N3)=O)=O)C(NC4=CC=CC=C4)=O)C2=O)=O)=O)CC1)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
プロトコル
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Subcutaneous Cell-Line-Derived Xenograft
Subcutaneous cell-line-derived xenograft (CDX) models are established by implanting cultured human cancer cell lines into immunodeficient mice, where the injected cells form localized tumors that can be monitored in vivo as a measure of tumorigenic potential, growth kinetics, and treatment response. These models are widely used in oncology research because they allow reproducible tumor formation and enable comparative assessment of tumor growth between different cell lines or genetic manipulations in a controlled in vivo microenvironment. Subcutaneous implantation of cancer cells in immunodeficient mice is a standard approach for evaluating tumor growth behavior and therapeutic response across multiple cancer types, including prostate, esophageal, pancreatic, and colon cancer models.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)