SXC2023
Based on 1 Customer Validation
SXC2023 is a glutamatergic reagent and cystine-glutamate antiporter (System xc−) activator. SXC2023 can affect SLC7A11. SXC2023 is applicable to the research of colorectal cancer and trichotillomania.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 99.85%
- CAS 番号: 1695562-36-7
- 分子式: C13H15NO4S
- 分子量:281.33
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保管条件:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
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溶剤 & 溶解度
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
SXC2023 binds to the ferroptosis suppressor protein SLC7A11 with a binding energy of -6.2 kcal/mol via multiple hydrogen bond, pi-stacking, and alkyl interactions, indicating potential to modulate SLC7A11 function and sensitize colorectal cancer cells to ferroptosis[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
化学情報
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CAS 番号 1695562-36-7
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性状 Solid
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分子量 281.33
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分子式 C13H15NO4S
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Color White to off-white
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SMILES
CC(N[C@H](C(O)=O)CSC(C1=CC=C(C=C1)C)=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
溶剤 & 溶解度
DMSO : 125 mg/mL (444.32 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
純度とドキュメンテーション
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データシート (271 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Ahmadizad Firouzjaei A, et al. Regulation of ferroptosis in colorectal cancer through therapeutic modulation and miRNA targeting. Biochem Biophys Rep. 2026;45:102444. Published 2026 Jan 8. [Content Brief]
[2]. CNS Summit: Selected Abstracts from the 2019 Meeting. Innov Clin Neurosci. 2019 Sep 1;16(9-10):S5-S19. [Content Brief]
[3]. Stein DJ, et al. Body-Focused Repetitive Behavior Disorders: From Competing Paradigms Toward Iterative Integration. Annu Rev Clin Psychol. 2026 May;22(1):481-503. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.5545 mL | 17.7727 mL | 35.5454 mL | 88.8636 mL |
| 5 mM | 0.7109 mL | 3.5545 mL | 7.1091 mL | 17.7727 mL | |
| 10 mM | 0.3555 mL | 1.7773 mL | 3.5545 mL | 8.8864 mL | |
| 15 mM | 0.2370 mL | 1.1848 mL | 2.3697 mL | 5.9242 mL | |
| 20 mM | 0.1777 mL | 0.8886 mL | 1.7773 mL | 4.4432 mL | |
| 25 mM | 0.1422 mL | 0.7109 mL | 1.4218 mL | 3.5545 mL | |
| 30 mM | 0.1185 mL | 0.5924 mL | 1.1848 mL | 2.9621 mL | |
| 40 mM | 0.0889 mL | 0.4443 mL | 0.8886 mL | 2.2216 mL | |
| 50 mM | 0.0711 mL | 0.3555 mL | 0.7109 mL | 1.7773 mL | |
| 60 mM | 0.0592 mL | 0.2962 mL | 0.5924 mL | 1.4811 mL | |
| 80 mM | 0.0444 mL | 0.2222 mL | 0.4443 mL | 1.1108 mL | |
| 100 mM | 0.0355 mL | 0.1777 mL | 0.3555 mL | 0.8886 mL |
SXC2023 関連分類
HY-W402682 関連分類
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