TAB29
TAB29 is a potent inhibitor of peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 (Pin1) with an IC50 of 874 nM, possesses therapeutic potential for human cancers.
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- CAS 番号: 2361144-71-8
- 分子式: C28H22O3
- 分子量:406.47
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
IC50:874 nM (Pin1)[1]
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| SK-HEP1 | IC50 |
1.14 μM
Compound: TAB29
|
Cytotoxicity against human SKHEP1 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human SKHEP1 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 31027708] |
| SNU-423 | IC50 |
2.732 μM
Compound: TAB29
|
Cytotoxicity against human SNU423 cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against human SNU423 cells assessed as reduction in cell viability by MTT assay
|
[PMID: 31027708] |
化学情報
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CAS 番号 2361144-71-8
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分子量 406.47
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分子式 C28H22O3
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SMILES
C1(OCC2=CC=CC=C2)=CC(OCC3=CC=CC=C3)=C4C(OC=C4C5=CC=CC=C5)=C1
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)