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Tilavonemab

(別名: ABBV-8E12; C2N-8E12)
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Based on 1 Customer Validation

Tilavonemab (ABBV-8E12) is a humanized anti-tau monoclonal antibody that binds to amino acids 25-30 near the N-terminus of the tau protein. Tilavonemab can block the ability of human and mouse neurons to uptake tau aggregates. Tilavonemab can be used for research on Alzheimer’s disease and other tauopathies.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

  • 保管条件:

    Please store the product under the recommended conditions in the Certificate of Analysis.

  • Experimental Validation Results for Tilavonemab
  • Experimental Validation Results for Tilavonemab
  • Experimental Validation Results for Tilavonemab
  • Tilavonemab Chemical Structure
    Tilavonemab 構造式
CAS 番号: 2096513-89-0
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To place orders, for customer services and technical support, please contact: MedChemExpress USA

Tel: 609-228-6898 E-mail: [email protected] [email protected]

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To place orders, for customer services and technical support, please contact:

609-228-6898
[email protected] [email protected]
最寄りの代理店をお探しください Your local distributor: Hycultec GmbHHycultec
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Assay Types
  • 1/16

    Human IgG4 kappa

  • 1/16

    Immobilized Human Tau Protein (His Tag) can bind Tilavonemab. The EC50 for this effect is 2.182 ng/mL.

  • 1/16

    Flow cytometric analysis of 1.5X106 SHSY5Y cells labeling Tilavonemab (HY-P99163, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa, Isotype Control (HY-P99003, blue) was used as the isotype control.

  • Tilavonemab Chemical Structure
    1/16
  • Tilavonemab
  • Immobilized Human Tau Protein (His Tag) can bind Tilavonemab. The EC50 for this effect is 2.182 ng/mL.
  • Flow cytometric analysis of 1.5X106 SHSY5Y cells labeling Tilavonemab (HY-P99163, red). Cells were fixed with 4% paraformaldehyde. Then stained with the primary antibody at 1/200 dilution for an hour at 4℃. Goat Anti-Human IgG H&L (AF488) (HY-P83776) was used as the secondary antibody at 1/1,000 dilution for 30 minutes at 4℃. Human IgG4 kappa, Isotype Control (HY-P99003, blue) was used as the isotype control.