TP-DEA2
TP-DEA2, a predictable-release Triptolide (HY-32735) prodrug, block Bleomycin-induced pulmonary fibrosis and inflammation. TP-DEA2 significantly inhibits α-SMA production.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- CAS 番号: 2871739-84-1
- 分子式: C25H34N2O7
- 分子量:474.55
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
生物活性
TP-DEA2 converts to Triptolide (TP) autonomously without the involvement of enzymes[1].
TP-DEA2 can inhibit the expression of a disintegrin and metalloproteinase 10 (ADAM 10) induced by TGF-β1 and reduce the secretion of a-SMA in fibroblasts[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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CAS 番号 2871739-84-1
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分子量 474.55
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分子式 C25H34N2O7
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SMILES
C[C@@]12[C@@]34[C@]5([C@@H]([C@@]6([C@](O6)([H])[C@]3([H])O4)C(C)C)OC(N(C)CCNC)=O)[C@@](C[C@@]1([H])C7=C(C(OC7)=O)CC2)([H])O5
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)