TPG-20A
TPG-20A is a SARS-CoV-2 main protease inhibitor with an IC50 of 27.8 nM. TPG-20A also inhibits MERS-CoV main protease. TPG-20A can be used for the research of infection, such as SARS-CoV-2.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 分子式: C24H27Cl2N5O5
- 分子量:536.41
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保管条件:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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生物活性
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化学情報
- 純度とドキュメンテーション
- 参考文献
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Help & FAQs
生物活性
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SARS-CoV-2 27.8 nM (IC50) |
TPG-20A (Compound 20a) shows EC50 values of 3.9 and 0.46 μM against SARS-CoV-2WK-521-exposed VeroE6 cells or SARS-CoV-2BQ.1.1-exposed HeLaACE2-TMPRSS2 cells[1].
TPG-20A shows CC50 values >100 μM against VeroE6 and HeLaACE2-TMPRSS2 cells[1].
TPG-20A shows IC50 values of 7.1 and 42.9 nM against SARS-CoV-2 Mpro and MERS-CoV Mpro[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
化学情報
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分子量 536.41
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分子式 C24H27Cl2N5O5
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SMILES
O=C(C(N1)=CC2=C1C=CC=C2OC)N[C@@H](CC(C)C)C(NN(C(C(Cl)Cl)=O)CC3=CC=CNC3=O)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
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保管条件
Please store the product under the recommended conditions in the Certificate of Analysis.
純度とドキュメンテーション
参考文献
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)
TPG-20A 関連分類
HY-178188 関連分類
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