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製品番号: HY-W721258

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Vaniliprole

Name: Vaniliprole
Brand: MedChemExpress
SKU: HY-W721258
Availability: PreOrder

(別名: MMV1794214)

Vaniliprole (MMV1794214) is a phenylpyrazole compound with anti-Toxoplasma gondii activity, with an EC₅₀ of 0.07 μM. Vaniliprole can be used in research related to parasitic infections.

商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。

CAS 番号: 145767-97-1
分子式: C₂₀H₁₀Cl₂F₆N₄O₂S
分子量:555.28

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

Vaniliprole 構造式

CAS 番号: 145767-97-1

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Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性
- 製品説明
- IC₅₀ & Target
- Cellular Effect
- 体外実験
化学情報
純度とドキュメンテーション
参考文献
Calculators
Help & FAQs
関連分類
Bioz

生物活性

製品説明

Vaniliprole (MMV1794214) is a phenylpyrazole compound with anti-Toxoplasma gondii activity, with an EC₅₀ of 0.07 μM. Vaniliprole can be used in research related to parasitic infections^[1]^[2].

IC₅₀ & Target

^[1]

Toxoplasma

0.07 μM (EC₅₀)

Parasite アイソフォーム固有の製品をすべて表示 :

Cellular Effect

Cell Line	Type	Value	Description	References
HFF	EC50	0.07 μM	Inhibition of intracellular Toxoplasma gondii RH-2F1 tachyzoite proliferation in human foreskin fibroblasts assessed by quantifying beta-galactosidase activity after 72 hrs incubation. Inhibition of intracellular Toxoplasma gondii RH-2F1 tachyzoite proliferation in human foreskin fibroblasts assessed by quantifying beta-galactosidase activity after 72 hrs incubation.	42660935
HFF	CC₅₀	>50 μM	Cytotoxicity against uninfected human foreskin fibroblasts assessed by resazurin reduction assay after 72 hrs incubation. Cytotoxicity against uninfected human foreskin fibroblasts assessed by resazurin reduction assay after 72 hrs incubation.	42660935

体外実験

Parasitic InfectionOthers

Parasitic Infection

Vaniliprole (MMV1794214) (1 μM; 72 h) exhibits anti-Toxoplasma gondii activity against intracellular RH-2F1 tachyzoites in HFF cells, inhibiting parasite growth by ≥80% at 1 μM^[1].
Vaniliprole exhibits potent anti-T. gondii activity against intracellular RH-2F1 tachyzoites in HFF cells with an EC₅₀ of 0.07 μM, and shows low cytotoxicity in uninfected HFFs with a CC₅₀ of greater than 50 μM, resulting in a selectivity index of >756^[1].

Others

Vaniliprole (compound C) derivatives exhibit larvicidal activity against Culex pipiens pallens^[2].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

CAS 番号 145767-97-1
分子量 555.28
分子式 C₂₀H₁₀Cl₂F₆N₄O₂S
SMILES

N#CC1=NN(C2=C(C=C(C(F)(F)F)C=C2Cl)Cl)C(/N=C/C3=CC=C(C(OC)=C3)O)=C1SC(F)(F)F
別名

MMV1794214
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Sun J, et al. Bis (trifluoromethylthio) carbene as a toolbox for versatile carbene transformations. Nature Communications. 2026 Jul 29.

[2]. Zhao Q, et al. Design, synthesis and insecticidal activity of novel phenylpyrazoles containing a 2,2,2-trichloro-1-alkoxyethyl moiety. Journal of agricultural and food chemistry. 2010 Apr 28;58(8):4992-8.

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

濃度濃度

体積体積

分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

体積 _(終了) 体積 _(終了)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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生物活性
- 製品説明
- IC₅₀ & Target
- 体外実験
化学情報
純度とドキュメンテーション
参考文献

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Vaniliprole

Parasite アイソフォーム固有の製品をすべて表示

生物活性

製品説明

IC₅₀ & Target

Cellular Effect

体外実験

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Bioz

Keywords

最近チェックした製品

Vaniliprole

Parasite アイソフォーム固有の製品をすべて表示

生物活性

製品説明

IC50 & Target

Cellular Effect

体外実験

化学情報

純度とドキュメンテーション

参考文献

Calculators

Help & FAQs

Vaniliprole 関連分類

HY-W721258 関連分類

Bioz

Keywords

最近チェックした製品

IC₅₀ & Target