(Z)-Azoxystrobin
Based on 1 Customer Validation
(Z)-Azoxystrobin is an enantiomer of Azoxystrobin. Azoxystrobin is an orally active, broad-spectrum β-methoxyacrylate fungicide. Azoxystrobin inhibits mitochondrial respiration by binding to the Qo site of the cytochrome bc1 complex and inhibiting electron transfer. Azoxystrobin induces the production of reactive oxygen species (ROS) and induces cell apoptosis.
商品は「研究用試薬」です。人や動物の医療用・臨床診断用・食品用の製品ではありません。
研究用途以外に使用した場合、当社は一切の責任を負いかねます。
- 純度: 98.10%
- CAS 番号: 143130-94-3
- 分子式: C22H17N3O5
- 分子量:403.39
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保管条件:
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
生物活性
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Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | CC50 |
>10 μM
Compound: MMV021057
|
Cytotoxicity against HEK293 cells (CO-ADD:MA_007); CC50 by cell viability assay in DMEM (10% FBS) media using TC plates, by Resazurin F(560/590)
Cytotoxicity against HEK293 cells (CO-ADD:MA_007); CC50 by cell viability assay in DMEM (10% FBS) media using TC plates, by Resazurin F(560/590)
|
10.6019/CHEMBL4296181 |
| L6 | IC50 |
50.32 μM
Compound: DNDI1511705
|
DNDI: Cytotoxicity against L-6 rat myoblasts from skeletal muscle cells
DNDI: Cytotoxicity against L-6 rat myoblasts from skeletal muscle cells
|
10.6019/CHEMBL1862790 |
| MRC5 | CC50 |
>28 μM
Compound: MMV021057
|
MRC5 CC50 (uM) Cytotoxicity
MRC5 CC50 (uM) Cytotoxicity
|
10.6019/CHEMBL3832761 |
化学情報
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CAS 番号 143130-94-3
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性状 Solid
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分子量 403.39
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分子式 C22H17N3O5
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Color Off-white to light brown
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SMILES
CO/C=C(C1=C(OC2=NC=NC(OC3=C(C=CC=C3)C#N)=C2)C=CC=C1)/C(OC)=O
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輸送条件
Room temperature in continental US; may vary elsewhere.
-
保管条件
-20°C, stored under nitrogen
* In solvent : -80°C, 6 months; -20°C, 1 month (stored under nitrogen)
純度とドキュメンテーション
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データシート (270 KB)
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SDS (624 KB)
- English - EN (624 KB)
- Français - FR (624 KB)
- Deutsch - DE (624 KB)
- Norwegian - NO (624 KB)
- Español - ES (624 KB)
- Swedish - SV (624 KB)
- Italian - IT (624 KB)
- Korean - KR (624 KB)
- Portuguese - PT (624 KB)
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取扱説明書 (2659 KB)
参考文献
[1]. Enock Mpofu, et al. Azoxystrobin amine: A novel azoxystrobin degradation product from Bacillus licheniformis strain TAB7. Chemosphere. 2021 Jun;273:129663. [Content Brief]
[4]. Zhang Q, et al. Oral azoxystrobin driving the dynamic change in resistome by disturbing the stability of the gut microbiota of Enchytraeus crypticus. J Hazard Mater. 2022 Feb 5;423(Pt B):127252. [Content Brief]
Calculators
濃度 (開始) × 体積 (開始) = 濃度 (終了) × 体積 (終了)