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製品番号: HY-186108

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ZY38

ZY38 is a SaClpP agonist that activates SaClpP-mediated α-casein hydrolysis with an EC₅₀ of 1.52 μM. ZY38 exhibits bactericidal activity against Staphylococcus aureus. ZY38 is applicable to studies related to Staphylococcus aureus infections, such as peritonitis.

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研究用途以外に使用した場合、当社は一切の責任を負いかねます。

分子式: C₂₈H₃₅F₃N₄O₃
分子量:532.60

保管条件:

Please store the product under the recommended conditions in the Certificate of Analysis.

ZY38 構造式

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

生物活性

製品説明

体外実験

ZY38 activates SaClpP-mediated α-casein hydrolysis in vitro with an EC₅₀ of 1.52 ± 0.2 μM^[1].
ZY38 inhibits the growth of S. aureus Newman in vitro with an MIC of 0.25 μg/mL^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

化学情報

分子量 532.60
分子式 C₂₈H₃₅F₃N₄O₃
SMILES

O=C(N(CCC1=O)[C@@]([H])(CN2CC3=C4C=CC=CC4=C(C)C=C3)N1[C@@H]([C@@H](C)CC)C2=O)NCCCC(F)(F)F
輸送条件

Room temperature in continental US; may vary elsewhere.
保管条件

Please store the product under the recommended conditions in the Certificate of Analysis.

純度とドキュメンテーション

取扱説明書 (2659 KB)

参考文献

[1]. Zhang T, et al. Structure-Guided Development of ClpP Agonists with Potent Therapeutic Activities against Staphylococcus aureus Infection. J Med Chem. 2025 Jan 23;68(2):1810-1823. [Content Brief]

Calculators

モル濃度計算機

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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分子量分子量

希釈計算機

濃度 _(開始) × 体積 _(開始) = 濃度 _(終了) × 体積 _(終了)

濃度 _(開始) 濃度 _(開始)

体積 _(開始) 体積 _(開始)

濃度 _(終了) 濃度 _(終了)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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