1. Epigenetics TGF-beta/Smad
  2. PKC
  3. K-252b

K-252b, an indolocarbazole isolated from the actinomycete Nocardiopsis, is a PKC inhibitor. K-252b can be used to inhibit extracellular kinases of cells in culture because it can’t pass through cell membrane freely .

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K-252b

K-252b Estructura química

No. CAS : 99570-78-2

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Descripciòn

K-252b, an indolocarbazole isolated from the actinomycete Nocardiopsis, is a PKC inhibitor. K-252b can be used to inhibit extracellular kinases of cells in culture because it can’t pass through cell membrane freely [1][2][3].

IC50 & Target

PKC[1].

Peso molecular

453.45

Fòrmula

C26H19N3O5

No. CAS
SMILES

C[C@@]([C@@]1(O)C(O)=O)(O[C@](N2C3=CC=CC=C43)([H])C1)N5C(C2=C4C6=C7CNC6=O)=C7C8=CC=CC=C58

Structure Classification
Initial Source

Nocardiopsis Sp.K-290

Envío

Room temperature in continental US; may vary elsewhere.

Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

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  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Nombre del producto:
K-252b
Cat. No.:
HY-N6734
Cantidad:
MCE Japan Authorized Agent: