1. Epigenetics
    TGF-beta/Smad
  2. PKC
  3. p32 Inhibitor M36

p32 Inhibitor M36 (Synonyms: M36)

Cat. No.: HY-124718 Purity: >98.0%
Handling Instructions

p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1.

For research use only. We do not sell to patients.

p32 Inhibitor M36 Chemical Structure

p32 Inhibitor M36 Chemical Structure

CAS No. : 802555-85-7

Size Price Stock Quantity
10 mM * 1 mL in DMSO USD 247 In-stock
Estimated Time of Arrival: December 31
5 mg USD 250 In-stock
Estimated Time of Arrival: December 31
10 mg USD 350 In-stock
Estimated Time of Arrival: December 31
25 mg USD 580 In-stock
Estimated Time of Arrival: December 31
50 mg USD 870 In-stock
Estimated Time of Arrival: December 31
100 mg USD 1300 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
500 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

Top Publications Citing Use of Products
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Description

p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1[1].

IC50 & Target

p32[1]

In Vitro

p32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC50 of 77.9 μM in complete media) and is much more potent under low glucose conditions with an IC50 of 7.3 μM[1].
p32 Inhibitor M36 is selective for p32 overexpressing cells[1].
p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC50 of 2.8 μM[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Molecular Weight

448.52

Formula

C₂₃H₂₈N₈O₂

CAS No.

802555-85-7

SMILES

O=C(NCCCNC(NC1=CC=CC(C2=NCCN2)=C1)=O)NC3=CC=CC(C4=NCCN4)=C3

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 5 mg/mL (11.15 mM; ultrasonic and warming and heat to 80°C)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 2.2296 mL 11.1478 mL 22.2956 mL
5 mM 0.4459 mL 2.2296 mL 4.4591 mL
10 mM 0.2230 mL 1.1148 mL 2.2296 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

p32 Inhibitor M36M36M 36M-36PKCProtein kinase CInhibitorinhibitorinhibit

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Product Name:
p32 Inhibitor M36
Cat. No.:
HY-124718
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