1. Epigenetics
    TGF-beta/Smad
  2. PKC
  3. p32 Inhibitor M36

p32 Inhibitor M36 (Synonyms: M36)

Cat. No.: HY-124718
Handling Instructions

p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1.

For research use only. We do not sell to patients.

p32 Inhibitor M36 Chemical Structure

p32 Inhibitor M36 Chemical Structure

CAS No. : 802555-85-7

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Description

p32 inhibitor M36 (M36) is a p32 mitochondrial protein inhibitor, which binds directly to p32 and inhibits p32 association with LyP-1[1].

IC50 & Target

p32[1]

In Vitro

p32 Inhibitor M36 inhibits SF188 glioma cells proliferation (IC50 of 77.9 μM in complete media) and is much more potent under low glucose conditions with an IC50 of 7.3 μM[1].
p32 Inhibitor M36 is selective for p32 overexpressing cells[1].
p32 Inhibitor M36 is also a potent inhibitor of patient-derived neurospheres with an IC50 of 2.8 μM[1].

Molecular Weight

448.52

Formula

C₂₃H₂₈N₈O₂

CAS No.

802555-85-7

SMILES

O=C(NCCCNC(NC1=CC=CC(C2=NCCN2)=C1)=O)NC3=CC=CC(C4=NCCN4)=C3

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Room temperature in continental US; may vary elsewhere

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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p32 Inhibitor M36
Cat. No.:
HY-124718
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