KCC2 Modulator-1
KCC2 Modulator-1 (example 52) is a KCC2 modulator. KCC2 Modulator-1 is used for the research of neurological disorders.
For research use only. We do not sell to patients.
- CAS No.: 2704531-36-0
- Formula: C35H41N5O3
- Molecular Weight:579.73
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
C50: 0.146 μM (KCC2)[1].
KCC2 is the only specific Cl- efflux transporter in mature neurons, which determines the inhibitory function of GABA; decreased expression/activity leads to neuronal hyperexcitability, making it a common core target for epilepsy, neuropathic pain and developmental encephalopathy.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 2704531-36-0
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Molecular Weight 579.73
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Formula C35H41N5O3
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SMILES
O=C1C2=C(CN1C(C)C)C(NC3=CC=C(C4=CC=C(OCCCCCC#C)C=C4)C=C3)=NC(N5CCOC(C6CC6)C5)=N2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
KCC2 Modulator-1 Related Classifications
HY-160081 Related Classifications
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