9-Nitrooleate
Based on 1 Customer Validation
9-Nitrooleate, a nitro fatty acid, is a nitro derivative of Oleic acid (HY-N1446). 9-Nitrooleate has potential for use in vascular disease research.
For research use only. We do not sell to patients.
- Purity: 99.79%
- CAS No.: 875685-44-2
- Formula: C18H33NO4
- Molecular Weight:327.46
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Storage:
Solution, -20°C, 2 years
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
1 μM
Compound: 42
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Agonist activity at human TRPA1 channel in HEK293 cells assessed as increase in intracellular calcium influx by radiometric Ca2+ imaging
Agonist activity at human TRPA1 channel in HEK293 cells assessed as increase in intracellular calcium influx by radiometric Ca2+ imaging
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[PMID: 20356305] |
9-Nitrooleate is formed by the reaction of NO with unsaturated fatty acids under oxidative stress conditions. 9-Nitrooleate belongs to a type of nitro-fatty acid. Nitro-fatty acids can exert anti-inflammatory and vascular protective effects by activating the PPARγ pathway or non-PPAR pathways. Especially in cardiovascular disease models, they can antagonize angiotensin II receptors and alleviate hypertension[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 875685-44-2
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Appearance Liquid
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Molecular Weight 327.46
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Formula C18H33NO4
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Color Colorless to light yellow
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SMILES
CCCCCCCC/C=C(CCCCCCCC(O)=O)/[N+]([O-])=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Solution, -20°C, 2 years
Purity & Documentation
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Data Sheet (263 KB)
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SDS (420 KB)
- English - EN (420 KB)
- Français - FR (420 KB)
- Deutsch - DE (420 KB)
- Norwegian - NO (420 KB)
- Español - ES (420 KB)
- Swedish - SV (420 KB)
- Italian - IT (420 KB)
- Korean - KR (420 KB)
- Portuguese - PT (420 KB)
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Handling Instructions (2659 KB)
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
9-Nitrooleate Related Classifications
HY-121457 Related Classifications
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