Potassium dihydrogen phosphate, AR,99.5%
Based on 1 Customer Validation
Potassium dihydrogen phosphate, AR,99.5% is a potassium salt. Potassium dihydrogen phosphate, AR,99.5% activates NF-κB. Potassium dihydrogen phosphate, AR,99.5% upregulates the expression of dental/osteogenic markers (OCN, DSP/DSPP, OSX, RUNX2, ALP) and enhances the mineralization capacity of human periodontal ligament stem cells. Potassium dihydrogen phosphate, AR,99.5% promotes the proliferation of human periodontal ligament stem cells in logarithmic growth phase. Potassium dihydrogen phosphate, AR,99.5% promotes the growth of somatic embryos of Dendrobium Sonia, increases leaf number, leaf length and fresh weight of tissue-cultured seedlings. Potassium dihydrogen phosphate, AR,99.5% is applicable to periodontal disease-related research.
For research use only. We do not sell to patients.
- Purity: 99.7%
- CAS No.: 7778-77-0
- Formula: KH2PO4
- Molecular Weight:136.08
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Storage:
Store at room temperature, keep dry and cool.
In solvent -80°C, 1 year , -20°C, 6 months
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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RUNX2 |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HEK293 | EC50 |
39 μM
Compound: 516951
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Substrate uptake by the Sodium-Dependent Phosphate Transport Protein 2A (NPT2a, SLC34A1) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC34A1 cells
Substrate uptake by the Sodium-Dependent Phosphate Transport Protein 2A (NPT2a, SLC34A1) as assessed by the fluorescent FLIPR membrane potential dye in HEK-293 JumpIN-SLC34A1 cells
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10.5281/zenodo.7355196 |
Potassium dihydrogen phosphate (1.8 mmol/L; treated on days 0, 1, 3, 5, 7, and 9) promotes the proliferation of PDLSCs in the logarithmic growth phase[1].
Potassium dihydrogen phosphate (1.8 mmol/L; 3 or 7 days) exerts no significant effect on the apoptosis rate of PDLSCs[1].
Potassium dihydrogen phosphate (1.8 mmol/L; 3 or 7 days) upregulates dentin/osteogenesis-related proteins in PDLSCs[1].
Potassium dihydrogen phosphate (180 mg/L) significantly promotes the growth of somatic embryo explants of *Dendrobium* 'Sonia' in MS medium. After 3 months of culture, each explant produces an average of 4.41 leaves with a leaf length of 1.16 cm, and the fresh weight of the tissue-cultured seedlings reaches 0.10 g[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:human periodontal ligament stem cells (PDLSCs)
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Concentration:1.8 mmol/L
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Incubation Time:3 d, 7 d
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Result:Increased the expression of odonto/osteogenic proteins (OCN, DSP, OSX, RUNX2, ALP) at day 3 and 7 compared to control (P < 0.05, P < 0.01).
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Cell Line:human periodontal ligament stem cells (PDLSCs)
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Concentration:1.8 mmol/L
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Incubation Time:3 d, 7 d
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Result:Increased the expression of odonto/osteogenic genes (OCN, DSP, OSX, RUNX2, ALP) at day 3 and 7 compared to control (P < 0.05, P < 0.01).
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Cell Line:human periodontal ligament stem cells (PDLSCs)
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Concentration:1.8 mmol/L
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Incubation Time:15 min, 30 min, 60 min, 120 min
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Result:Down-regulated IκBα expression, reaching minimum at 30 min (P < 0.01).
Up-regulated nuclear P65 expression at 60 min (P < 0.01).
| NCT Number | Sponsor | Condition | Start Date |
Phase
|
|---|---|---|---|---|
| NCT01329991 | Plexxikon| | 2011-05 | PHASE1 |
Chemical Information
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CAS No. 7778-77-0
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Appearance Solid
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Molecular Weight 136.08
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Formula KH2PO4
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Color Colorless to off-white
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SMILES
O=P(O[O])=O.[KH2]
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Store at room temperature, keep dry and cool
In solvent -80°C 1 year -20°C 6 months
Solvent & Solubility
H2O : 50 mg/mL (367.43 mM; ultrasonic and warming and heat to 60°C)
DMSO : < 1 mg/mL (insoluble or slightly soluble)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (274 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 1 year; -20°C, 6 months. When stored at -80°C, please use it within 1 year. When stored at -20°C, please use it within 6 months.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| H2O | 1 mM | 7.3486 mL | 36.7431 mL | 73.4862 mL | 183.7155 mL |
| 5 mM | 1.4697 mL | 7.3486 mL | 14.6972 mL | 36.7431 mL | |
| 10 mM | 0.7349 mL | 3.6743 mL | 7.3486 mL | 18.3715 mL | |
| 15 mM | 0.4899 mL | 2.4495 mL | 4.8991 mL | 12.2477 mL | |
| 20 mM | 0.3674 mL | 1.8372 mL | 3.6743 mL | 9.1858 mL | |
| 25 mM | 0.2939 mL | 1.4697 mL | 2.9394 mL | 7.3486 mL | |
| 30 mM | 0.2450 mL | 1.2248 mL | 2.4495 mL | 6.1238 mL | |
| 40 mM | 0.1837 mL | 0.9186 mL | 1.8372 mL | 4.5929 mL | |
| 50 mM | 0.1470 mL | 0.7349 mL | 1.4697 mL | 3.6743 mL | |
| 60 mM | 0.1225 mL | 0.6124 mL | 1.2248 mL | 3.0619 mL | |
| 80 mM | 0.0919 mL | 0.4593 mL | 0.9186 mL | 2.2964 mL | |
| 100 mM | 0.0735 mL | 0.3674 mL | 0.7349 mL | 1.8372 mL |
* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.
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