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Cat. No.: HY-120794

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SC-67655

SC 67655 is a potent and stable pentapeptide MHC class II haplotype DR4 (DR4 Dw4 or DRB 1"0401) ligand with an IC₅₀ of 50 nM. SC 67655 can be used for the study of autoimmune diseases.

For research use only. We do not sell to patients.

CAS No.: 182134-00-5
Formula: C₃₇H₆₂N₆O₉
Molecular Weight:734.92

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

SC-67655 Chemical Structure

CAS No.: 182134-00-5

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

Description

SC 67655 is a potent and stable pentapeptide MHC class II haplotype DR4 (DR4 Dw4 or DRB 1"0401) ligand with an IC₅₀ of 50 nM. SC 67655 can be used for the study of autoimmune diseases^[1].

All TNF Receptor Isoforms :

Chemical Information

CAS No. 182134-00-5
Molecular Weight 734.92
Formula C₃₇H₆₂N₆O₉
Sequence

(S)-{CBA-Val-Pec}-Asp-Pro-Thr-NH-{n-Pr}
Sequence Shortening

(S)-{CBA-Val-Pec}-APT-NH-{n-Pr}
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. S L Woulfe, et al. A peptidomimetic that specifically inhibits human leukocyte antigen DRB1*0401-restricted T cell proliferation. J Pharmacol Exp Ther. 1997 May;281(2):663-9. [Content Brief]

[2]. Gunnar J. Hanson, et al. (1996). Design of MHC class II (DR4) ligands using conformationally restricted imino acids at p3 and p5. , 6(16), 1931-1936.

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Biological Activity
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Chemical Information
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SC-67655

All TNF Receptor Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

SC-67655 Related Classifications

HY-120794 Related Classifications