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Cat. No.: HY-112805

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ST8154AA1

ST8154AA1 is a part of antibody agent conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity.

For research use only. We do not sell to patients.

CAS No.: 2247025-59-6
Formula: C₃₆H₅₁N₅O₈S
Molecular Weight:713.88

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (265 KB)

ST8154AA1 Chemical Structure

CAS No.: 2247025-59-6

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

ST8154AA1 is a part of antibody agent conjugates (ADCs) charged with HDAC inhibitor by a linker, shows antitumor activity^[1].

IC₅₀ & Target

Traditional Cytotoxic Agents

All Drug-Linker Conjugates for ADC Isoforms :

Chemical Information

CAS No. 2247025-59-6
Molecular Weight 713.88
Formula C₃₆H₅₁N₅O₈S
SMILES

OC([C@H]1CC[C@H](CNC(CCCCCN2C(CC(SCCCCC[C@H](NC([C@H]3CCC(N3)=O)=O)C(NC4=CC=CC=C4)=O)C2=O)=O)=O)CC1)=O
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Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Cini E, et al. Antibody drug conjugates (ADCs) charged with HDAC inhibitor for targeted epigenetic modulation. Chem Sci. 2018 Jul 3;9(31):6490-6496. [Content Brief]

Calculators

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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ST8154AA1

All Drug-Linker Conjugates for ADC Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

ST8154AA1 Related Classifications

HY-112805 Related Classifications