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Cat. No.: HY-160552

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244cis

Name: 244cis
Brand: MedChemExpress
SKU: HY-160552
Price: 70.00 USD
Availability: InStock
Rating: 5 (1 reviews)

고객리뷰

Based on 1 Customer Validation

244cis, a piperazine-containing ionizable cationic lipid, has been used to generate lipid nanoparticles (LNPs). LNPs containing 244cis and coated with mRNA reporter gene were specifically accumulated in mouse lungs compared with LNPs containing SM-102. Induces a decrease in serum chemokine (C-C motif) ligand 2 (CCL2) levels.

연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.

Purity : 99.67%
CAS No.: 2956402-64-3
화학식: C₆₀H₁₁₁N₃O₆
분자량:970.54

보관:

Solution, -20°C, 2 years

244cis Chemical Structure

CAS No.: 2956402-64-3

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity

제품 설명

Chemical Information

CAS No. 2956402-64-3
Appearance Liquid
분자량 970.54
화학식 C₆₀H₁₁₁N₃O₆
Color Colorless to light yellow
SMILES

CCCCCC/C=C\COC(CCCCCCCCN(CCCCCCCCC(OC/C=C\CCCCCC)=O)CCN1CCN(CC1)CCCCCCCCC(OC/C=C\CCCCCC)=O)=O
선적

Room temperature in continental US; may vary elsewhere.
보관

Solution, -20°C, 2 years

용액&용해도

In Vitro:

Ethanol : 50 mg/mL (51.52 mM; Need ultrasonic)

View the Complete Stock Solution Preparation Table

순도&문서

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (265 KB)
SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Kim M, et al. Novel piperazine-based ionizable lipid nanoparticles allow the repeated dose of mRNA to fibrotic lungs with improved potency and safety. Bioeng Transl Med. 2023 May 28;8(6):e10556. [Content Brief]

Calculators

몰농도 계산기

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

농도 희석 계산기

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Complete Stock Solution Preparation Table

Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.

Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg
Ethanol	1 mM	1.0304 mL	5.1518 mL	10.3035 mL	25.7589 mL
	5 mM	0.2061 mL	1.0304 mL	2.0607 mL	5.1518 mL
	10 mM	0.1030 mL	0.5152 mL	1.0304 mL	2.5759 mL
	15 mM	0.0687 mL	0.3435 mL	0.6869 mL	1.7173 mL
	20 mM	0.0515 mL	0.2576 mL	0.5152 mL	1.2879 mL
	25 mM	0.0412 mL	0.2061 mL	0.4121 mL	1.0304 mL
	30 mM	0.0343 mL	0.1717 mL	0.3435 mL	0.8586 mL
	40 mM	0.0258 mL	0.1288 mL	0.2576 mL	0.6440 mL
	50 mM	0.0206 mL	0.1030 mL	0.2061 mL	0.5152 mL

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MOQ

Minimum order quantity

100 mg

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