3,4-Dephostatin

(Synonyms: Methyl-3,4-dephostatin)

3,4-Dephostatin (Methyl-3,4-dephostatin) is an inhibitor of protein-tyrosine phosphatase (PTPase). 3,4-Dephostatin accelerates nerve growth factor (NGF)-induced neurite formation in PC12h cells. 3,4-Dephostatin sustains the NGF-induced tyrosine phosphorylation of proteins, most prominently that of mitogen-activated protein (MAP) kinase. 3,4-Dephostatin also prolongs epidermal growth factor (EGF)-induced tyrosine phosphorylation and activation of MAP kinase.

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  • CAS No.: 173043-84-0
  • 화학식: C7H8N2O3
  • 분자량:168.15
  • 보관:

    Please store the product under the recommended conditions in the Certificate of Analysis.

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