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3-Hydroxy Midostaurin

(Synonyms: CGP52421)
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3-Hydroxy Midostaurin (CGP 52421), a metabolite of PKC412, effectively inhibits FMS-like tyrosine kinase-3 (FLT3) autophosphorylation with IC50s of approximately 132 nM and 9.8 μM in culture medium and plasma, respectively. 3-Hydroxy Midostaurin is less selective but more cytotoxic than PKC412.

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  • Purity: 98.18%
  • CAS No.: 179237-49-1
  • 화학식: C35H30N4O5
  • 분자량:586.64
  • 보관:
    Powder   -20°C, 3 years , 4°C, 2 years ; In solvent   -80°C, 6 months , -20°C, 1 month
  • 3-Hydroxy Midostaurin Chemical Structure
    3-Hydroxy Midostaurin Chemical Structure
CAS No.: 179237-49-1
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  • 3-Hydroxy Midostaurin Chemical Structure
    3-Hydroxy Midostaurin Chemical Structure
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  • 3-Hydroxy Midostaurin