4'-Methoxyflavone
Based on 1 Customer Validation
4'-Methoxyflavone is a flavonoid with antioxidant properties and anti-proliferative activity against cancer cells. 4'-Methoxyflavone can inhibit cycle-dependent kinases leading to cell cycle arrest and regulate cell signaling pathways to influence cell proliferation and apoptosis. 4'-Methoxyflavone can be used in cancer chemoprevention research.
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- Purity: 99.63%
- CAS No.: 4143-74-2
- 화학식: C16H12O3
- 분자량:252.26
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보관:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
Cellular Effect
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BTI-TN-5B1-4 | IC50 |
27.87 μM
Compound: 3d
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Inhibition of human recombinant MAOB expressed in BTI-TN-5B1-4 cells by para-tyramine oxidation assay
Inhibition of human recombinant MAOB expressed in BTI-TN-5B1-4 cells by para-tyramine oxidation assay
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[PMID: 20045650] |
| MCF7 | GI50 |
61.8 μM
Compound: 1e
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Cytotoxicity against Homo sapiens (human) MCF7 cells after 48 hr by SRB assay
Cytotoxicity against Homo sapiens (human) MCF7 cells after 48 hr by SRB assay
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10.1007/s00044-012-0423-1 |
| MDCK | CC50 |
191.8 μM
Compound: 1f
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Cytotoxicity against dog MDCK cells assessed as reduction in cell viability by MTT assay
Cytotoxicity against dog MDCK cells assessed as reduction in cell viability by MTT assay
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[PMID: 31744778] |
| MDCK | EC50 |
9.36 nM
Compound: 1f
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Antiviral activity against Influenza A virus (H1N1) infected in dog MDCK cells assessed as reduction in log2HA titer incubated for 3 to 4 days by CPE assay
Antiviral activity against Influenza A virus (H1N1) infected in dog MDCK cells assessed as reduction in log2HA titer incubated for 3 to 4 days by CPE assay
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[PMID: 31744778] |
| MOLT-4 | GI50 |
99.2 μM
Compound: 1e
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Cytotoxicity against Homo sapiens (human) MOLT4 cells after 48 hr by SRB assay
Cytotoxicity against Homo sapiens (human) MOLT4 cells after 48 hr by SRB assay
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10.1007/s00044-012-0423-1 |
Chemical Information
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CAS No. 4143-74-2
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Appearance Solid
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분자량 252.26
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화학식 C16H12O3
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Color White to off-white
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SMILES
O=C1C=C(C2=CC=C(OC)C=C2)OC3=CC=CC=C13
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Structure Classification
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Initial Source
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 10 mg/mL (39.64 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (269 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.9642 mL | 19.8208 mL | 39.6416 mL | 99.1041 mL |
| 5 mM | 0.7928 mL | 3.9642 mL | 7.9283 mL | 19.8208 mL | |
| 10 mM | 0.3964 mL | 1.9821 mL | 3.9642 mL | 9.9104 mL | |
| 15 mM | 0.2643 mL | 1.3214 mL | 2.6428 mL | 6.6069 mL | |
| 20 mM | 0.1982 mL | 0.9910 mL | 1.9821 mL | 4.9552 mL | |
| 25 mM | 0.1586 mL | 0.7928 mL | 1.5857 mL | 3.9642 mL | |
| 30 mM | 0.1321 mL | 0.6607 mL | 1.3214 mL | 3.3035 mL |
4'-Methoxyflavone Related Classifications
HY-139054 Related Classifications
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