6-Hydroxyisatin
Based on 1 Customer Validation
6-Hydroxyisatin is an atrial natriuretic peptide receptor (ANP receptor) inhibitor. 6-Hydroxyisatin exhibits inhibitory activity against ANP-stimulated particulate guanylyl cyclase activity in rat brain cell membranes.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity : 95.86%
- CAS No.: 116569-08-5
- 화학식: C8H5NO3
- 분자량:163.13
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Biological Activity
제품 설명
In Vitro
6-Hydroxyisatin (50 μM) inhibits ANP-stimulated particulate guanylyl cyclase activity in rat brain membranes by 54.4%[2].
6-Hydroxyisatin (50 μM) inhibits ANP-stimulated particulate guanylyl cyclase activity in rat heart membranes by 16.7%[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 116569-08-5
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Appearance Solid
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분자량 163.13
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화학식 C8H5NO3
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Color Orange to red
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SMILES
O=C1NC2=C(C=CC(O)=C2)C1=O
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Structure Classification
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Initial Source
Micromonospora carbonacea
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
용액&용해도
In Vitro:
DMSO : 2 mg/mL (12.26 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (272 KB)
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SDS (394 KB)
- English - EN (394 KB)
- Français - FR (394 KB)
- Deutsch - DE (394 KB)
- Norwegian - NO (394 KB)
- Español - ES (394 KB)
- Swedish - SV (394 KB)
- Italian - IT (394 KB)
- Korean - KR (394 KB)
- Portuguese - PT (394 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 6.1301 mL | 30.6504 mL | 61.3008 mL | 153.2520 mL |
| 5 mM | 1.2260 mL | 6.1301 mL | 12.2602 mL | 30.6504 mL | |
| 10 mM | 0.6130 mL | 3.0650 mL | 6.1301 mL | 15.3252 mL |
6-Hydroxyisatin Related Classifications
HY-W092067 Related Classifications
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Keywords
- 6-Hydroxyisatin
- 116569-08-5
- Natriuretic Peptide Receptor (NPR)
- Natriuretic Peptide Receptor
- NPR
- NPR-A
- NPR-B
- NPR-C
- DFT
- rat brain membranes
- atrial natriuretic peptide receptors
- keto/phenol tautomerism
- atrial natriuretic peptide
- rat heart membranes
- Sandmeyer’s procedure
- UV/Vis absorption
- Streptomyces sp. strain B1848
- particulate guanylyl cyclase
- Inhibitor
- inhibitor
- inhibit